A simple sensor based on 1,8-naphthalimide with large Stokes shift for detection of hypochlorous acid in living cells

Jiao, Chunpeng; Liu, Yuanyuan; Lu, Wenjuan; Zhang, Pingping; Ma, Xiaolu; Wang, Yanfeng

doi:10.1039/c9ra06174f

Cited by 12 publications

(2 citation statements)

References 46 publications

(43 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, the naphthalimide compounds have been applied to detect different metal ions such as Cu 2+ , Zn 2+ , Hg 2+ , Ag + , Fe 3+ , Cr 3+ , or fluoride ion [ 13 , 22 , 23 , 24 , 25 ]. Also, naphthalimide derivatives were explored successfully for monitoring hypochlorous acid and hypochlorite [ 26 , 27 , 28 ]. Some naphthalimide-based fluorescent compounds were developed for detecting hydrogen sulfide, formaldehyde, or phosgene [ 29 , 30 , 31 , 32 ].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Solvent Dependent Fluorescence of Some Piperidine-Substituted Naphthalimide Derivatives and Consequences for Water Sensing

Tigoianu

Airinei

Georgescu

et al. 2022

IJMS

View full text Add to dashboard Cite

Novel fluorescent strigolactone derivatives that contain the piperidine-substituted 1,8-naphthalimide ring system connected through an ether link to a bioactive 3-methyl-furan-2-one unit were synthesized and their spectroscopic properties investigated. The solvatochromic behavior of these piperidine-naphthalimides was monitored in solvents of different polarity using the electronic absorption and fluorescence spectra. These compounds exhibited a strong positive solvatochromism taking into account the change of solvent polarity, and the response mechanism was analyzed by fluorescence lifetime measurements. According to Catalan and [f(n), f(ε), β, α] solvent scales, the dipolarity and polarizability are relevant to describe the solute–solvent interactions. The emission chemosensing activity was discussed in order to determine the water content in organic environments. The emission intensity of these compounds decreased rapidly in dioxane, increasing water level up to 10%. Measuring of quantum yield indicated that the highest values of quantum efficiency were obtained in nonpolar solvents, while in polar solvents these derivatives revealed the lowest quantum yield. The fluorescence decay can be described by a monoexponential model for low water levels, and for higher water contents a biexponential model was valid.

show abstract

Section: Introductionmentioning

confidence: 99%

Synthesis and Solvent Dependent Fluorescence of Some Piperidine-Substituted Naphthalimide Derivatives and Consequences for Water Sensing

Tigoianu

Airinei

Georgescu

et al. 2022

IJMS

View full text Add to dashboard Cite

show abstract

“…To date, numerous fluorescent probes for ClO À have been reported. [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Most of these fluorescence probes for ClO À were a type of short wavelength response probes. Such probes have some prominent disadvantages, such as strong background effect, shallow imaging depth, and poor anti-infection ability.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, fluorescence property and cell imaging of a perylene diimide-based NIR fluorescent probe for hypochlorite with dual-emission fluorescence responses

Cheng

Qian

et al. 2020

Mater. Adv.

View full text Add to dashboard Cite

show abstract

Temperature-controlled synthesis of hollow, porous gold nanoparticles with wide range light absorption

et al. 2020

View full text Add to dashboard Cite

An easy synthesis method of hollow, porous gold nanoparticles (AuHP NPs) with controlled diameter and pores sizes and with a wide range of light absorbance (continuous between 500 and 900 nm) is presented together with the explanation of the nanoparticle formation mechanism. The NPs were investigated using transmission electron microscopy (TEM) combined with the selected area electron diffraction patterns, X-ray diffraction and ultraviolet-visible spectroscopy. TEM images showed that changing the synthesis temperature allows to obtain AuHP NPs with sizes from 35 ± 4 nm at 60°C to 76 ± 8 nm at 90°C. The effects of nanoscale porosity on the far-and near-field optical properties of the nanoparticles, as well as on effective conversion of electromagnetic energy into thermal energy, were applied in simulated photothermal cancer therapy. The latter one was simulated by irradiation of two cancer cell lines SW480 and SW620 with lasers operating at 650 nm and 808 nm wavelengths. The mortality of cells after using the synthesized AuHP NPs as photosensitizers is between 20 and 50% and increases with the decrease in the diameter of the AuHP NPs. All these attractive properties of the AuHP NPs make them find application in many biomedical studies.

show abstract

A simple sensor based on 1,8-naphthalimide with large Stokes shift for detection of hypochlorous acid in living cells

Abstract: Probe 1 shows excellent selectivity to HOCl among different ions including common ROS, high sensitivity, high fluorescence quantum yield (Φ = 0.93), low detection limit (0.237 μM) and successfully used for the detection of HOCl in cells.

Cited by 12 publications

References 46 publications

Synthesis and Solvent Dependent Fluorescence of Some Piperidine-Substituted Naphthalimide Derivatives and Consequences for Water Sensing

Synthesis and Solvent Dependent Fluorescence of Some Piperidine-Substituted Naphthalimide Derivatives and Consequences for Water Sensing

Synthesis, fluorescence property and cell imaging of a perylene diimide-based NIR fluorescent probe for hypochlorite with dual-emission fluorescence responses

Temperature-controlled synthesis of hollow, porous gold nanoparticles with wide range light absorption

Contact Info

Product

Resources

About