A Simple One‐Pot Organometallic Formylation/Trapping Sequence Using N‐Formylcarbazole.

Abstract

Reactions of organo-metal compounds Reactions of organo-metal compounds O 0350A Simple One-Pot Organometallic Formylation/Trapping Sequence Using N-Formylcarbazole. -The reaction of N-formyl carbazole (I) with organometallic reagents generates metastable anionic carbazole carbinol salts. These salts release aldehydes which are trapped in situ by a second nucleophile forming α,β-unsaturated esters (IV) and (VII) or the alcohols (X). -(DIXON*, D. J.; LUCAS, A. C.; Synlett 2004, 6, 1092-1094; Univ. Chem. Lab., Cambridge Univ., Cambridge CB2 1EW, UK; Eng.) -Mais 38-063