A Simple Mathematical Approach to Calculate Blood Loss in Radical Prostatectomy

Abstract

Introduction: The aim of this study was to apply a simple mathematical approach to calculate blood loss in 126 patients undergoing radical retropubic prostatectomy (RRP). Materials and Methods: Perioperative red blood cell loss (RBCL) was estimated by adding the difference in circulating red blood cells from before to after surgery to the allogeneic red blood cells transfused in the same period. Results: Mean preoperative hematocrit was 45 ± 4% and mean perioperative RBCL was 574 ± 297 ml, corresponding to a mean equivalent whole blood loss (WBL) of 1,479 ± 831 ml. Twenty of 126 patients (15.9%) received 42 units of allogeneic packed red blood cells (PRBC), for a mean of 2.1 ± 1.2 U/patient. The transfusion rate was higher in patients with a preoperative hematocrit of 40% or less (45 vs. 13%, p = 0.014). Conclusions: Anatomical RRP is still associated with appreciable operative blood loss. Owing to the high preoperative hematocrit values, the allogeneic blood transfusion rate is low and the transfusion requirement of the majority of patients is limited to about 2 units of PRBC. Preoperative autologous blood augmentation strategies may not be routinely needed for patients with a basal hematocrit of >40%.

Retrospective analysis of autologous blood use in bimaxillary repositioning osteotomy surgery: a quality improvement study

“…Therefore, a logarithmic equation favored by several authors 16‐18 was used, considering the preoperative baseline data of sex, weight, height, and Hct. In , the calculation of MBL (V max ) is as follows: EBV = patient's blood volume (calculated from sex, weight, and height according to Nadler et al 18‐20 …”

Comparison of common perioperative blood loss estimation techniques: a systematic review and meta-analysis

“…Thus, three different formulas are used in the literature to calculate the total blood volume of patients. The Moore formula [75,76], which, like Nadler's formula [75][76][77][78][79][80][81] takes into account height, weight and sex for the calculation, and the ICSH formula [75,76], which uses gender and body surface area to calculate the total blood volume. The formula according to Nadler was used most often in the literature.…”

Efficacy of Tranexamic acid in Reducing Blood Loss During Maxillofacial Trauma Surgery–A Pilot Study

“…Blood loss was calculated as the difference in pre and postoperative haemoglobin and hematocrit values. The following formulae were used assuming the blood volume was normalized at 48 hours postoperatively and the haemoglobin level could be raised by 1 g/ dL for every pack of red blood cells transfused: [18,22]). maintain a therapeutically effective concentration between 5 mg/ dl.…”