A Simple Electrocardiogram Marker for Risk Stratification of Ischemic Stroke in Low-resources Settings

Soliman, Elsayed Z.; Juma, Hadge; Nkosi, Nelson

doi:10.1016/j.jstrokecerebrovasdis.2009.07.007

Cited by 12 publications

(8 citation statements)

References 20 publications

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“…Nine publications were excluded, because they were letters to the editor, editorials, or reviews; provided insufficient data; or did not examine the defined end points. Ten studies, including 8 data sets on PTFV1, [1][2][3][8][9][10]22,23 6 data sets on maximum PWD, 1,2,8,9,24,25 and 3 data sets on maximum PWA, 1,8,9 were included in this meta-analysis. [1][2][3][8][9][10][22][23][24][25] The ECG appearances of these indices are depicted in Figure 2.…”

Section: Search Resultsmentioning

confidence: 99%

“…Moreover, 4 studies studied PTFV1 as a categorical variable, and the pooled meta-analysis showed that the higher PTFV1 conferred an ≈59% increase in stroke risk. 2,3,10,23 Of the 4 studies, 1 failed to demonstrate a statistically significant effect in the overall population. 3 The authors of this study showed that PTFV1 interacted with age, and for subjects aged >60 years, abnormal PTFV1 conferred a >2-fold increase in the risk of incident stroke in multivariate analysis adjusted for sex, history of stroke or transient ischemic attack, ischemic heart disease or diabetes mellitus, baseline creatinine, and in-treatment systolic blood pressure.…”

Section: August 2017mentioning

confidence: 99%

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P-Wave Indices and Risk of Ischemic Stroke

Tse

Korantzopoulos

et al. 2017

Stroke

106

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Background and Purpose-Atrial cardiomyopathy is associated with an increased risk of ischemic stroke. P-wave terminal force in lead V 1 , P-wave duration, and maximum P-wave area are electrocardiographic parameters that have been used to assess left atrial abnormalities related to developing atrial fibrillation. The aim of this systematic review and metaanalysis was to examine their values for predicting ischemic stroke risk. Methods-PubMed and EMBASE databases were searched until December 2016 for studies that evaluated the association between P-wave indices and stroke risk. Both fixed-and random-effects models were used to calculate the overall effect estimates. Results-Ten studies examining P-wave terminal force in lead V 1 , P-wave duration, and maximum P-wave area were included. P-wave terminal force in lead V 1 was found to be an independent predictor of stroke as both a continuous Key Words: atrial fibrillation ◼ electrocardiography ◼ heart atria ◼ odds ratio ◼ stroke P-Wave Indices and Risk of Ischemic Stroke

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Section: Search Resultsmentioning

confidence: 99%

Section: August 2017mentioning

confidence: 99%

P-Wave Indices and Risk of Ischemic Stroke

Tse

Korantzopoulos

et al. 2017

Stroke

106

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“…Stroke in sub-Saharan Africa is a major public health problem, with higher mortality than in developed countries and occurrence at a younger age [1][2][3] . The rates of the disease which were considerably lower, are now rapidly increasing, even doubling in regions such as rural South Africa [4][5] .…”

Section: Introductionmentioning

confidence: 99%

Stroke subtypes and factors associated with ischemic stroke in Kinshasa, Central Africa

Tshikwela¹,

Londa²,

Tongo³

2015

Afr H. Sci.

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Background and Purpose: Ischemic stroke causes death and disability worldwide. Better understanding and controlling factors associated will improve the prevention of the disease. This study reviews records of patients with ischemic stroke in Central Africa. Material and methods: Patients of Bantu ethnicity with clinical diagnosis of stroke and lesion on computed tomography scan from January 2011 to December 2012 were selected. Computed tomographic subtypes of ischemic stroke and factors associated were considered with tropical seasonal variation. Results: Of the 303 first-ever stroke patients (average age 53 years old, range 3-84 years old; 62% male) were included in the study. The prevalence of computed tomography stroke subtypes was: lacunar infarct (63%) and non lacunar infarct lesion (37%). Silent brain infarct was seen in 9 % of patients. Prevalence of factors associated with ischemic stroke was: age≥60 years old (55%); male gender (63%), chronic and uncontrolled hypertension (54%) and type 2 Diabetes mellitus (11%). A seasonal high prevalence was observed in warmer season (p < 0.05). Conclusions: This study shows a high prevalence of lacunar infarct than non lacunar in Bantu of Central Africa.

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“…PTF had the highest positive predictive value of our ECG findings, and should therefore raise a suspicion of cardioembolism in a young stroke patient. Atrial enlargement is an early marker of heart disease in hypertensive patients and PTF also acts as a high-risk marker for incident stroke [13,14,20]. Both LVH and atrial stress due to congestive heart failure, which was present in 6% of our patients, are the most likely explanations for the high prevalence of PTF in our series.…”

Section: Discussionmentioning

confidence: 64%

“…We applied the ECG criteria by Sokolow-Lyon (SV1 + RV5 / 6 ≥ 3.5 mV) to define left ventricular hypertrophy [12]. P-terminal force (PTF) was defined as the terminal negative part of the P-wave in lead V1 having an amplitude deeper than − 0.1 mV and a duration of at least 40 ms [13,14] (See Fig. 2).…”

Section: Ecg Analysismentioning

confidence: 99%