A Simple Chemical Route toward High Surface Area CeO₂ Nanoparticles Displaying Remarkable Radical Scavenging Activity

Abstract

This work reports a simple chemical route to synthesize high surface area ceria (CeO2) nanoparticles which exhibit remarkable radical scavenging activity. Synthesized CeO2 nanoparticles are characterized by thermogravimetric analysis (TGA), X‐ray diffraction (XRD), Fourier‐transform infrared spectroscopy (FTIR) and Raman spectroscopy, scanning electron microscopy (SEM), energy‐dispersive X‐ray analysis (EDX), transmission electron microscopy (TEM), and Brunauer‐Emmett‐Teller surface area (BET surface area) analyses. The characterization results reveal the formation of cubic phase of CeO2 with particles sizes of 10 nm and a remarkably high specific surface area of 236.8 m2/g. The nanoparticles are explored for 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) and hydroxyl radical scavenging activity that is to assess the antioxidant property of nanoceria by in‐vitro spectrophotometric approach.

Manganese-doped cerium oxide nanocomposite as a therapeutic agent for MCF-7 adenocarcinoma cell line

“…2 . The obtained 2θ values of 28.6°, 33.0°, 47.5°, 56.4°, 59.3°, and 69.5° are attributable to the (1 1 1), (2 0 0), (2 2 0), (3 1 1), (2 2 2), and (4 0 0) planes, respectively, similarly as described in previous reports ( Saikia et al, 2017 ). The ionic radius of Ce 4+ (1.03 Å) is larger than that of Mn 2+ (0.74 Å) and, therefore, the latter ions can substitute the former in the CeO 2 crystal lattice.…”

Synthesis, characterization and in vitro cytotoxicity study of Co and Ni ferrite nanoparticles prepared by sol-gel method

“…For example, the toxic effect for CeO 2 NPs was related to with increased oxidative stress [16,17]. On the other hand, the antioxidant effect of CeO 2 NPs plays a protective role in the body by eliminating free oxygen radicals [18]. However, the toxicity of nanoparticles is one of the limiting factors for their successful application in medicine.…”

Interrelationships between the structural, spectroscopic, and antibacterial properties of nanoscale (< 50 nm) cerium oxides

“…Figure 4 presents the nitrogen adsorption–desorption isotherms, and the corresponding Barrett-Joyner-Halenda (BJH) pore size distributions for the synthesised cerium oxide nanoparticles. Nanoparticles exhibiting pore diameters in the 2–50 nm range are considered mesoporous in nature 61 . The adsorption–desorption isotherms illustrate type-IV isotherm curves with H3-type hysteresis loops, which are characteristics of mesoporous structured nanoparticles containing slit-like pores 62 , 63 .…”