A simple and sensitive approach for the electrochemical determination of amaranth by a Pd/GO nanomaterial-modified screen-printed electrode

Tajik, Somayeh; Beitollahi, Hadi; Jang, Ho Won; Shokouhimehr, Mohammadreza

doi:10.1039/d0ra08723h

Cited by 20 publications

(1 citation statement)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The rapid development of nanotechnology has led to introducing optimized diagnostic systems through the design of biomedical tools, especially biosensors. − Among the various biosensors, the combination of aptamer and electrochemical strategies to create aptasensors is attracting noticeable attention due to the high aptamer affinity to its individual target. In addition to the excellent selectivity, the electrochemical aptasensors have high sensitivity and ease of operation. − In a conventional electrochemical aptasensor, the aptamer immobilizes on the electrode surface and the bio-recognition between the target and aptamer leads to the comprehensible electrochemical signals for analysis.…”

Section: Introductionmentioning

confidence: 99%

Two-Dimensional Mesoporous Copper Hydroxide Nanosheets Shelled on Hollow Nitrogen-Doped Carbon Nanoboxes as a High Performance Aptasensing Platform

Roushani

Hosseini

Pakzad

et al. 2021

ACS Sustainable Chem. Eng.

View full text Add to dashboard Cite

The design of metal hydroxide nanosheets on hollow carbonaceous nanostructures has attracted immense attention because of their unparalleled physical/chemical properties with sizeable intrinsic capability to load specific chemicals. Herein, a novel metal hydroxide based on hollow nitrogen-doped carbon nanoboxes shelled with a nanoporous copper hydroxide nanosheet (Cu(OH)2@N–C n-box) was fabricated. The structure of fabricated hollow nanomaterials was fully characterized by various physicochemical characterization techniques such as field emission scanning electron microscopy (FESEM), high-resolu1tion transmission electron microscopy (HRTEM), Brunauer–Emmett–Teller (BET) method, thermogravimetric analysis (TGA), powder X-ray diffraction (XRD), and Fourier-transform infrared (FTIR) and Raman spectroscopies, which confirmed that a complex core–shell structure with ordered two-dimensional Cu(OH)2 nanostructures on N–C n-box was successfully prepared. The Cu(OH)2@N–C n-box is used to fabricate an advanced electrochemical aptasensor to measure the protein enzyme trypsin. In addition, it acts as an excellent substrate with abundant functional groups and a large surface area for fixing and bonding aptamers on the modified glass-carbon surface. Each step of electrode surface modification was investigated through ferro/ferri cyanide probe signal changes. The designed aptasensor can determine trypsin in a linear concentration between 10 to 80 pg/mL and 10 to 80 ng/mL with a detection limit of 3 pg/mL. The proposed system also has a desirable selectivity in the presence of different interferences. This is the first report on the rational design of hollow carbonaceous materials hybridized Cu(OH)2 for the electrochemical application.

show abstract