A simple and efficient fluorophoric probe for dual sensing of Fe³⁺and F⁻: application to bioimaging in native cellular iron pools and live cells

Abstract

A quinoline functionalized fluorophore exhibited high selectivity towards Fe3+ ions and the ligand–metal complex showed excellent selectivity towards F− ions.

Off–On, Ratiometric, and On–Off Fluorescence Responses of Thioether‐Linked Bisquinolines toward Hg2+ and Fe3+ Ions

“…[27][28][29][30][31] On the other hand, the development of sensors for Fe 3+ ions is also of significant interest. [32][33][34][35][36][37][38][39][40] Iron is an indispensable element in living organisms and plays many important roles in biological processes including oxygen transport and enzymatic oxidative molecular transformations. As its deficiency and overload both cause serious problems, the iron content in living systems needs to be maintained in the proper range.…”

A highly selective multi-responsive fluorescence sensor for Zn2+ based on a diarylethene with a 4,6-dimethylpyrimidine unit

“…[7][8][9] However, the abnormal accumulation of Zn 2+ within the body could create serious health issues, such as myopathy, Alzheimer's disease, epileptic seizures, encephalopathy, and various cancers. 10,11 Consequently, it is highly desirable for developing effective ways for monitoring Zn 2+ , 12 which would provide an effective and promising approach to study its physiological and pathological processes. 13 The usual detection procedures include traditional techniques, such as, chromatography, voltammetric and ion selective electrodes.…”

A novel boronic acid-based fluorescent sensor for selectively recognizing Fe3+ ion in real time

“…As an important component for the formation of hemoglobin, myoglobin and various enzymes, Fe 3+ ion participates in many biological and chemical processes at the cellular level and plays an important role in transporting oxygen and nutrients in the blood. [1][2][3] A lack or excess of Fe 3+ ion may lead to low immunity, reduced intelligence and reduced anti-infective capacity, affecting the body's ability to regulate body temperature, and even inducing a variety of diseases, such as Alzheimer's disease, Parkinson's syndrome and other neurodegenerative diseases. [4][5][6] In daily life, Fe 3+ ion is added to many foods, health care products, fertilizers and pesticides to promote its absorption by humans and crops.…”

“…), carbohydrates [24][25][26][27] and so on. Compared with sensing other transition metals such as Cu 2+ and Hg 2+ , there are relatively less uorescent sensors of Fe 3+ ion, which are based on derivatives of macrocyclic molecules, 2,28 rhodamines, [29][30][31][32][33][34] coumarin, [35][36][37] quinoline, 1,[38][39][40] etc. However, most Fe 3+ ion sensors reported have irreversible recognition, 30,41 long response time, 1,29,36,42 poor water solubility, 28,42,43 and are susceptible to interference from other transition metal ions such as Zn 2+ , Cr 3+ and Pb 2+ .…”