A Simple and Effective Glycine‐Catalyzed Procedure for the Preparation of Oximes.

Maheswara, Muchchintala; Siddaiah, Vidavalur; Gopalaiah, Kovuru; Rao, Vallabhaneni Madhava; Rao, C. Venkata

doi:10.1002/chin.200645031

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“…The long-range correlation observed between H-1′′ (δH 5.22) and C-3 (δC 135.3) indicated the glucosyl group was located at C-3. The glucosyl group should be in a β-configuration due to the coupling constant value of H-1′′ (J = 7 Hz) 13 and by comparing the 1 H and 13 C NMR data with those of glucose 11 . Furthermore, this was also confirmed by ROESY correlations of H-1′′ with H-3′′ and H-5′′, H-2′′ with H-4′′.…”

Section: Resultsmentioning

confidence: 99%

A New Flavone from Flower Buds of Rosa rugosa

Qin¹,

Yang²,

Xia³

et al. 2014

Asian J. Chem.

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Rosa rugosa Thunb. (Rosaceae) is a common ornamental flower distributed in the temperate regions of eastern Asia and widely cultivated in the Yunnan Province 1,2. The petals and buds of R. rugosa are often used as food, incense and as Chinese medicinal materials for the treatment of stomachache, diarrhea and gynecological problems 3. Previous studies have shown the presence of tannins 4 , terpenoids 5-7 and flavonoids 8,9 in this genus. Anti-inflammatory and cytotoxic activities have been observed with selected chemical ingredients isolated from R. rugosa 7,10. Previous studies in our laboratories on this plant have led to the isolation of three new aurones that possess anti-HIV-1 and cytotoxic properties 9. Continuing the effort to search for novel and bioactive metabolites from medicinal plants, we now report the isolation and characterization of a new flavone (1). In this paper, the structure elucidation of 1 and its biological evaluation are described. EXPERIMENTAL Optical rotations were measured with a Horiba SEPA-300 polarimeter. UV spectra were obtained using a Shimadzu UV-2401A spectrophotometer. A Tenor 27 spectrophotometer was used for scanning IR spectra. 1D-and 2D NMR spectroscopic data were recorded on a DRX-500 NMR spectrometer with TMS as internal standard. Chemical shifts (δ) are expressed in ppm with reference to the TMS signal. HRESIMS was performed on a VG Autospec-3000 spectrometer. Semipreparative HPLC was performed on a Shimadzu LC-8A preparative liquid chromatograph with Zorbax PrepHT GF

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Section: Resultsmentioning

confidence: 99%