A Short Review on Proteomics and its Applications

Chandrasekhar, K.; Dileep, A.; Lebonah, D. Ester; Kumari, J. Pramoda

doi:10.56431/p-avsz0g

Cited by 10 publications

(19 citation statements)

References 9 publications

(9 reference statements)

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“…In complex pesticide biodegradation, proteomics stands as an important tool, unraveling the patterns, functions, and interactions of proteins [157]. This omics approach not only unravels the identity of potential enzymes and metabolic pathways linked to pesticide degradation but also uncovers the intricate protein pathways activated in response to pesticide-induced damage.…”

Section: Proteomicsmentioning

confidence: 99%

Phytomicrobiomes: A Potential Approach for Sustainable Pesticide Biodegradation

Salam,

Mahmood,

Asghar

et al. 2024

Applied Sciences

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Globally, pest-induced crop losses ranging from 20% to 40% have spurred the extensive use of pesticides, presenting a double-edged sword that threatens not only human health but also our environment. Amidst various remediation techniques, bioremediation stands out as a compelling and eco-friendly solution. Recently, the phytomicrobiome has garnered increasing attention as endophytic microbes, colonizing plants from their roots, not only foster plant growth but also enhance the host plant’s resilience to adverse conditions. Given the persistent demand for high crop yields, agricultural soils often bear the burden of pesticide applications. Biodegradation, the transformation of complex pesticide compounds into simpler forms through the activation of microbial processes and plant-based enzymatic systems, emerges as a pivotal strategy for restoring soil health. Manipulating the phytomicrobiome may emerge as a viable solution for this purpose, offering a native metabolic pathway that catalyzes pollutant degradation through enzymatic reactions. This review delves into the pivotal role of phytomicrobiomes in the degradation of diverse pesticides in soil. It explores contemporary innovations and paves the way for discussions on future research directions in this promising field.

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Section: Proteomicsmentioning

confidence: 99%

Phytomicrobiomes: A Potential Approach for Sustainable Pesticide Biodegradation

Salam,

Mahmood,

Asghar

et al. 2024

Applied Sciences

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“…Isolating germ cells by type (as by STAPUT 63,64 or FACS sorting 65,66 ) or conducting analyses on select developmental stages may serve to reduce background from unwanted cell types. Further, the development of more detailed reference databases 67 and advances in analysis software [68][69][70][71] may reduce these barriers.…”

Section: Proteomics and Transcriptomicsmentioning

confidence: 99%

Modern tools applied to classic structures: Approaches for mammalian male germ cell RNA granule research

Chukrallah

Snyder

2022

Andrology

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First reported in the 1800s, germ cell granules are small nonmembrane bound RNA‐rich regions of the cytoplasm. These sites of critical RNA processing and storage in the male germ cell are essential for proper differentiation and development and are present in a wide range of species from Caenorhabditis elegans through mammals. Initially characterized by light and electron microscopy, more modern techniques such as immunofluorescence and genetic models have played a major role in expanding our understanding of the composition of these structures. While these methods have given light to potential granule functions, much work remains to be done. The current expansion of imaging technologies and omics‐scale analyses to germ cell granule research will drive the field forward considerably. Many of these methods, both current and upcoming, have considerable caveats and limitations that necessitate a holistic approach to the study of germ granules. By combining and balancing different techniques, the field is poised to elucidate the nature of these critical structures.

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“…This Special Issue, “Mass Spectrometric Proteomics 2.0”, presents the second volume of a series dedicated to the dissemination of results obtained from the application of MS-based proteomics across different areas. Although not all problems in MS proteomics have been solved, this is currently a mature technique that has prompted the publication of thousands of articles in the biochemical sector to date [ 1 ]. That being said, the question arises as to whether the release of a “new” series on proteomics would make sense.…”

mentioning

confidence: 99%