A Severe Case ofArthrographis kalraeKeratomycosis

Abstract

A 52-year-old man with diabetes developed a unilateral central corneal ulcer after accidental foreign body inoculation. He complained of pain and loss of visual acuity in the injured eye, which displayed redness and edema and eventually discharged pus. A corneal scraping from the left eye orbit revealed fungal elements, and cultures of the material grew a fungus. The isolate was identified as Arthrographis kalrae based on gross and microscopic morphologies. The patient received amphotericin B intravenously and itraconazole orally. The wound healed following surgical intervention, but the patient lost the use of his left eye.

Detection of <i>Trichophyton</i> spp. from footwear of patients with tinea pedis

“…We think that Acremonium was the cause of infection in this patient due to the fact that the scales were obtained after the patient's skin was almost entirely disinfected with ethanol and the same filamentous fungus was collected from the patient's shoe. In addition to Acremonium, several kinds of fungi that cause skin mycoses and onychomycosis were detected and identified among the shoes, e.g., Arthrographis (13) and Fusarium (14), as shown in Table 2. The rate of infection increases, especially in immunocompromised persons, when mold, including Trichophyton spp., grows abundantly in environments such as shoes.…”

First case of Arthrographis kalrae fungemia in a patient with cystic fibrosis

“…Currently, one case of infection with Arthrographis sp. and 14 cases of infection with A. kalrae have been reported (Table 1): two onychomycosis [2], [3], one mycetoma [4], five keratitis [5], [6], [7], [8], [9] one of which associated with sinusitis [8], two knee joint infection [10], [11], one endocarditis [12], two pulmonary infections [13], [14], one meningitis [15] and one fungal stroke [16]. These cases have a worldwide distribution: seven cases in Europe, one in China, one in Japan, three in USA, one in Mexico, one in Malaysia and one in Australia.…”