A sesquiterpenoid with plant growth regulatory activity fromSaussurea lappa

Talwar, K. K.; Singh, Inder Pal; Kalsi, P. S.

doi:10.1016/0031-9422(91)83069-w

Cited by 35 publications

(23 citation statements)

References 4 publications

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“…22-Dihydrostigmasterol (Jain and Banks, 1968) and sesquiterpenoides (Maurer and Grieder, 1977) were reported from costus root oil. Saussureal (a sesquiterpenoid) (Talwar et al, 1991), steroids, pregnenolone, ␤-sitosterol, daucosterol, a phenylpropanoid glycoside, syrine, a lignan glycoside, 1-hydroxypinoresinol-1-␤-d-glucopyranoside, 12-octadecadienoic acid, (Z,Z)-9,12-octadienoic acid-2-hydroxy-1,3-propanedinyl ester (Yang et al, 1997c), seven noncytotoxic compounds including two novel sesquiterpenes, a guaianolidetype with a C17 skeleton, lappalone and 1␤, 6␣-dihydroxycostic acid ethyl ester were isolated (Sun et al, 2003). Subsequently, Jung et al (1998) investigated shikokiols, the cytotoxic components of crude extract of Saussurea lappa root.…”

Section: Conditions Methods Of Applications Referencementioning

confidence: 99%

Saussurea costus: Botanical, chemical and pharmacological review of an ayurvedic medicinal plant

Pandey

Rastogi

Rawat

2007

Journal of Ethnopharmacology

189

129

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Section: Conditions Methods Of Applications Referencementioning

confidence: 99%

Saussurea costus: Botanical, chemical and pharmacological review of an ayurvedic medicinal plant

Pandey

Rastogi

Rawat

2007

Journal of Ethnopharmacology

189

129

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“…Refluxed in benzene solution with TsOH, 57a afforded a-santenolide (57d). Formation of 57d from 57a involves a ring expansion via a Wagner -Meerwein shift of the ring residue to afford a carbocation 57c, which gives 57d by loss of a proton [70].…”

Section: Saussurea Ussuriensismentioning

confidence: 99%

Secondary Metabolites of Plants from the Genus Saussurea: Chemistry and Biological Activity

Wang

Dong

et al. 2010

Chemistry & Biodiversity

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The Asteraceae family comprises ca. 1000 genera, mainly distributed in Asia and Europe. Saussurea DC., as the largest subgenus of this family, comprises ca. 400 species worldwide, of which ca. 300 species occur in China. Most plants in China grow wild in the alpine zone of the Qingzang Plateau and adjacent regions at elevations of 4000 m. Plants of the genus Saussurea (Asteraceae) are used in both traditional Chinese folk medicine and Tibet folklore medicine, since they are efficacious in relieving internal heat or fever, harmonizing menstruation, invigorating blood circulation, stopping bleeding, alleviating pain, increasing energy, and curing rheumatic arthritis. A large number of biologically active compounds have been isolated from this genus. This review shows the chemotaxonomy of these compounds (215 compounds) such as sesquiterpenoids (101 compounds), flavonoids (19 compounds), phytosterols (15 compounds), triterpenoids (25 compounds), lignans (32 compounds), phenolics (23 compounds), and chlorophylls (11 compounds). Biological activities (anti-inflammatory, anticancer, antitumor, hepatoprotective, anti-ulcer, cholagogic, immunosuppressive, spasmolytic, antimicrobial, antiparasitic, antifeedant, CNS depressant, antioxidant, etc.) of these compounds, including structure-activity relationships, are also discussed.

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“…Its chemical constituents have been studied by some groups. The main chemical and bioactive constituents of this plant are sesquiterpenes and sesquiterpene lactones [2,3]. In order to clarify the medicinal value of Saussurea lappa and to search for biologically active compounds, we have reinvestigated the chemical constituents of this plant.…”

Section: Introductionmentioning

confidence: 99%