A SERS-based lateral flow immunochromatographic assay using Raman reporter mediated-gap AuNR@Au nanoparticles as the substrate for the detection of enrofloxacin in food samples

Gold Nanoparticle-Coated Magnetic Graphene Oxide as a Dual-Mode Immunochromatographic Biosensor for Enrofloxacin Residue Analysis in Food Samples

“…It has broad-spectrum activity against Gram-negative and Gram-positive bacteria. , Due to advantages like high efficiency, low toxicity, a wide antibacterial spectrum, a small crossover of drug resistance, and a low price, the drug is widely used in livestock, poultry, and aquaculture processes. , However, its prolonged or excessive use can lead to drug residues in animal products, which can pose a threat to the health of consumers by inducing endocrine system disorders, nerve damage, and drug resistance to bacteria in the body. − The Ministry of Agriculture of the People’s Republic of China released the national standard for maximum veterinary residue limits in food in September 2022 (GB 31650.1–2022), and the maximum detection limit of ENR is 10 μg/kg. Therefore, the development of a biosensor for convenient and efficient detection of ENR residues is very important . The traditional ENR detection methods include liquid chromatography tandem mass spectroscopy, high-performance thin-layer chromatography, capillary electrophoresis, and other methods.…”

“…Therefore, the development of a biosensor for convenient and efficient detection of ENR residues is very important. 8 The traditional ENR detection methods include liquid chromatography tandem mass spectroscopy, 9 high-performance thin-layer chromatography, 10 capillary electrophoresis, 11 and other methods. Although these methods have satisfactory sensitivity and reliability, they require expensive equipment, maintenance costs, complex and time-consuming operations by professional operators to complete the measurement, and they also require professional statistics and analysis of the data.…”

Preparation of Hybrid Magnetic Nanoparticles for Sensitive and Rapid Detection of Phorate Residue in Celery Using SERS Immunochromatography Assay

“…The combination of SERS and ICA has been proven to effectively improve the sensitivity and capability of quantitative analysis compared with traditional ICA methods [ 41 ]. So far, SERS-ICA has been developed for the detection of various targets [ 42 , 43 ], but the sensitive detection of phorate is yet to be reported.…”