A Seroepidemiologic Study of Infectious Mononucleosis

Lehane, Daniel E.

doi:10.1001/jama.1970.03170260036009

Cited by 42 publications

(3 citation statements)

References 11 publications

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“…The sero-prevalence of EBV varies widely by geographic location, developed countries carry a lower burden of sero-prevalence than the developing ones. Primary EBV infection occurs at a younger age among persons from lower versus higher socioeconomic backgrounds [13,14]. Most of the children (67%) in this study were younger than 6 years old.…”

Section: Discussionmentioning

confidence: 66%

Childhood infectious mononucleosis

Skenderi¹,

Sulovari²,

Kuli-Lito³

et al. 2023

World J. Adv. Res. Rev.

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Epstein-Barr virus (EBV) is a human herpesvirus that is ubiquitous in nature, and most of the world population is infected by it. Infectious Mononucleosis (IM) is the most common clinical syndrome caused by EBV. This study was conducted to valuate epidemiological and clinical features of Infectious Mononucleosis caused by EBV in children. In it were enrolled 107 children 0-14 years old hospitalized with the diagnosis of Infectious Mononucleosis. Children ranged from 8-months old to 12.5years old, median age was 4.74 years. Fever was the most prominent feature in 97% of cases followed by lymphadenitis and pharyngitis in 79% and 78% of cases. Hepatitis was found in 55% of children. Classic syndrome of Infectious Mononucleosis was more prevalent in older children. Conclusively the probability of developing Infectious Mononucleosis after primary EBV infection correlates with age, young children are often moderately ill, presenting with atypical or partial Infective Mononucleosis syndrome.

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Section: Discussionmentioning

confidence: 66%

Childhood infectious mononucleosis

Skenderi¹,

Sulovari²,

Kuli-Lito³

et al. 2023

World J. Adv. Res. Rev.

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“…Later Henle et al (7) provided Serologic evidence of the relationship between this virus and infectious mononucleosis. Several studies have corroborated this association (10,11) and it is not unlikely that the EBV is the etiologic agent of infectious mononucleosis. This agent, however, has also been linked to African Burkitt's lymphoma (6), carcinoma of the posterior nasal space (7) and sarcoidosis (9).…”

Section: Discussionmentioning

confidence: 87%

“…This is also the case with cytomegalovirus infections in allograft recipients, ost infections giving no symptoms (14). In addlt' lon, the EBV appears to cause only minor or sUbc~inical infection in the majority of normal, preViously healthy individuals attacked (10).…”

Section: Discussionmentioning

confidence: 92%

Antibodies to the Epstein‐barr Virus in Kidney Transplant Recipients

Spencer¹,

Andersen²

1972

Journal of Internal Medicine

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Changes in antibody titer against the Epstein‐Barr virus (EBV), the apparent cause of infectious mononucleosis, have been surveyed in 30 patients, randomly selected from kidney transplant recipients in Aarhus during the last five years. Sera taken at transplantation and at approximately 1, 2, 3 and 5 to 12 months post‐transplant were examined for antibodies against EBV using an indirect immunofluorescence technique with EB‐3 cells. Anti‐EBV antibody, and thereby evidence of past infection, was found in all but one set of sera. In three patients a significant, fourfold, rise in antibody titer was observed. One, a man of 31, had a transient illness with fever, sore throat and enlarged lymph nodes in association with antibody changes; another, a girl of 18, had two snort febrile periods of unexplained etiology; the third. a girl of 11, had no recorded symptoms.

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Infectious Mononucleosis and the Epstein-Barr Virus

Rapp¹

1978

Arch Pediatr Adolesc Med

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A Seroepidemiologic Study of Infectious Mononucleosis

Cited by 42 publications

References 11 publications

Childhood infectious mononucleosis

Childhood infectious mononucleosis

Antibodies to the Epstein‐barr Virus in Kidney Transplant Recipients

Infectious Mononucleosis and the Epstein-Barr Virus

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