A Series of Novel N,N‐Donor Ligands with Binaphthyl Backbones

Abstract

Chiral ligands with the 1,1′‐binaphthyl unit as the backbone play an important role in enantioselective catalysis. In this paper we present the synthesis and characterization of three novel azole‐functionalized 1,1‐binaphthyl derivatives. These systems are accessible from commercially available starting materials in not more than four steps. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

Trinuclear Diamagnetic Nickel(II) Complexes with Bridging 3‐Arylpyrazolato Ligands

“…We recently extended the strategy discussed above by using enantiomerically pure 2,2′‐bis[3(5)‐pyrazolyl]‐1,1′‐binaphthyl, which contains two 3(5)‐arylpyrazolyl units. This compound forms a hydrogen‐bound double trimer with a pelton‐wheel‐like structure in the solid state3 that is preserved after exchange of the bridging N–H protons with M + ions (M = Cu, Ag, or Au) 4. Meyer et al recently extended this concept to an octanuclear Au 4 –Ag 4 compound: by applying 3,5‐bis(phenylthiomethyl)‐1 H ‐pyrazole, they managed to obtain a compound with four Au + centers bridged by four pyrazolato ligands and were able to coordinate four additional Ag + ions to the thioether units in the outer‐sphere of the gold/pyrazolato core 5.…”

Design, synthesis, and structure–activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element

“…Compounds 14a-14f were methylated with iodomethane to obtain the target compounds 15 and 16. [13][14][15] For obtaining the derivatives 18a-18e and 21a-21d with substituents at different positions of triazole, two synthetic routes were used; as depicted in Scheme 2. The compounds 18a-18e were obtained by converting compound 17 using different hydrazides followed by dehydration of 12a.…”

Gold(i) complexes with heteroaryl phosphine ligands

“…The exhibition of intermolecular hydrogen bonds between pyrazoles including a proton donor and a proton acceptor site in one molecule often results in the generation of hydrogen bonded trimers and tetramers. [48][49][50][51] The formation of the dimer found in the solid state structure of compound 1 is quite a rare example. Both 3 and 4 crystallize in the triclinic space group P1 ˉwith one molecule each in the asymmetric unit.…”