A series of new heteroleptic Hg(II) complexes: Synthesis, crystal structures and photophysical properties

Synthesis, spectral properties,in vitroα‐glucosidase inhibitory activity and quantum chemical calculations of novel mixed‐ligand M(II) complexes containing 1,10‐phenanthroline

“…Due to the electron‐rich heteroaromatic rings of such derivatives, such as 1,10‐phenanthroline (phen), 2,2′‐bipyridyl, etc., they are commonly used in the fields of coordination and material chemistry . These ligands also occupy an important place in the design of complexes containing transition metals for interpretation of the role of metal ions role in biological inorganic systems . Moreover, the synthesis and luminescent, molecular and magnetic properties of some coordination polymers based on phenanthroline ligands, phthalate and bipyridinyl co‐ligands have been reported …”

“…[6,7] These ligands also occupy an important place in the design of complexes containing transition metals for interpretation of the role of metal ions role in biological inorganic systems. [8][9][10] Moreover, the synthesis and luminescent, molecular and magnetic properties of some coordination polymers based on phenanthroline ligands, phthalate and bipyridinyl co-ligands have been reported. [11,12] It is estimated that the prevalence of type 2 diabetes mellitus depending on insulin resistance will increase to approximately 5% in all age groups globally within the next 15 years.…”

Synthesis, DFT calculations, α‐glucosidase inhibitor activity, and docking studies on Schiff base metal complexes containing isothiocyanate

“…It is known that complexes of heteroatom-containing molecules are analog to some substrate with enzyme complexes in our body in terms of structural, spectroscopic and catalytic properties, [45][46][47][48] not only synthesis and design of different coordination complexes of nitrogencontaining heterocyclic structures/pseudohalides (such as N-(pyridin-2-ylmethylene)methanamine, 2,2 0 -bipyridyl, 1,10-phenanthroline, thiocyanate, isothiocyanate, and azide), but also the investigation of their physicochemical properties such as nonlinear optics, catalysis, luminescence are of great importance in terms of examining biological and pharmaceutical activities. [38][39][40][41][42][43][44][49][50][51][52][53][54][55][56][57][58][59][60][61][62] Besides, the pseudohalides, NCS/SCN, and N 3 were reported to coordinate with metal ions in both bridging and terminal modes. [58][59][60][61][62] Considering the results obtained in the literature and our previous studies, it was seen that the αglucosidase inhibitory activities of the complexes including Hg, Cd, Mn, Ag, Co, Cu, Ni, and Zn metals were at the micromolar level.…”