Volume 4: Advanced Manufacturing Processes; Biomedical Engineering; Multiscale Mechanics of Biological Tissues; Sciences, Engin 2012
DOI: 10.1115/esda2012-82326
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A Sensitivity Study on a Hybrid FE/MB Human Middle Ear Model

Abstract: The human middle ear includes the tympanic membrane and the ossicular chain. The finite element method is capable of representing the complex geometry and the material orthotropy of the tympanic membrane. On the contrary, the ossicles can be considered as rigid bodies and a multi-body approach can be adopted. In the present study a multi-body model of the ossicular chain and other structures (joints, ligaments and muscle tendons) of the middle ear was developed and combined with a finite element model of the t… Show more

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Cited by 2 publications
(3 citation statements)
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“…Models including also, at least, the middle ear were developed by Kelly et al [2], by Koike et al [3], by Gan et al [4] to [6] and Lee an Chen [7]. In the last years, hybrid FE and multi-body models of the TM and middle ear were also proposed by the present authors [8] and [9].…”
Section: Introductionmentioning
confidence: 79%
“…Models including also, at least, the middle ear were developed by Kelly et al [2], by Koike et al [3], by Gan et al [4] to [6] and Lee an Chen [7]. In the last years, hybrid FE and multi-body models of the TM and middle ear were also proposed by the present authors [8] and [9].…”
Section: Introductionmentioning
confidence: 79%
“…Investigators have applied phase‐sensitive optical coherence tomography in animals 98 and human cadaver models 99 . Good estimates of the normal and pathologic TM, and ossicular chain mechanical properties have been obtained 97,100–115 . However, imaging of soft and bony tissues with high spatial resolution for highly accurate models remains a challenge 116 .…”
Section: Middle Earmentioning
confidence: 99%
“…99 Good estimates of the normal and pathologic TM, and ossicular chain mechanical properties have been obtained. 97,[100][101][102][103][104][105][106][107][108][109][110][111][112][113][114][115] However, imaging of soft and bony tissues with high spatial resolution for highly accurate models remains a challenge. 116 Several imaging methods have been investigated, including micro-computed tomography (micro-CT), 117,118 orthogonal plane fluorescence optical sectioning, 118 and accurate serial section imaging.…”
Section: Anatomy and Physiologymentioning
confidence: 99%