A Sensitivity Analysis to the Role of the Fronto‐Parietal Suture in <i>Lacerta Bilineata</i>: A Preliminary Finite Element Study

Moazen, Mehran; Bruner, Emiliano

doi:10.1002/ar.22629

Cited by 15 publications

(24 citation statements)

References 62 publications

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“…Local strain at these specific locations is returned, but inferring either strain over the whole skull or the function of patent sutures is problematic. FEA allows stresses and strains to be predicted for the entire structure [36–44], and anatomical features to be controlled so that the influence of patent or fused sutures can be explored [45–51]. Moazen et al .…”

Section: Introductionmentioning

confidence: 99%

Cranial sutures work collectively to distribute strain throughout the reptile skull

Curtis

Jones

Evans

et al. 2013

J. R. Soc. Interface.

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The skull is composed of many bones that come together at sutures. These sutures are important sites of growth, and as growth ceases some become fused while others remain patent. Their mechanical behaviour and how they interact with changing form and loadings to ensure balanced craniofacial development is still poorly understood. Early suture fusion often leads to disfiguring syndromes, thus is it imperative that we understand the function of sutures more clearly. By applying advanced engineering modelling techniques, we reveal for the first time that patent sutures generate a more widely distributed, high level of strain throughout the reptile skull. Without patent sutures, large regions of the skull are only subjected to infrequent low-level strains that could weaken the bone and result in abnormal development. Sutures are therefore not only sites of bone growth, but could also be essential for the modulation of strains necessary for normal growth and development in reptiles.

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Section: Introductionmentioning

confidence: 99%

Cranial sutures work collectively to distribute strain throughout the reptile skull

Curtis

Jones

Evans

et al. 2013

J. R. Soc. Interface.

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“…Indeed, both the frontal‐parietal and the palatine‐pterygoid joint of the lacertid species are highly interdigitated, probably preventing any flexion or extension movements of a certain magnitude. However, computational model studies (see Moazen et al, ) are expected to better elucidate the stiffness degree of various interdigitated sutures. Interestingly, a similar interdigitation at the frontal‐parietal joint was found also in Cryptolacerta hassiaca , a lacertid‐like lizard fossil from Germany which provided a first morphological evidence for lacertid‐amphisbaenians monophyly on the basis of a shared reinforced and akinetic skull (Müller et al, ).…”

Section: Discussionmentioning

confidence: 99%

To Move or Not to Move: Cranial Joints in European Gekkotans and Lacertids, an Osteological and Histological Perspective

Mezzasalma

Maio

Guarino

2013

The Anatomical Record

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Lepidosaurs are frequently described as having highly kinetic skulls, and different forms of cranial kinesis have been described as being characteristic of their radiation. The model of amphikinesis proposed by Frazzetta, J Morphol 1962; 111:287-319, which was long considered a synapomorphy of the large suborder Sauria, is now much debated given its uncertain distribution among the various lizard taxa and the lack of data about its morphological correlates. In this article, we analyze the anatomical correlates of different forms of cranial kinesis, with particular regard to the putative saurian amphikinesis, describing the possible diverse skull movements of several species of European gekkotans (Hemidactylus turcicus, Mediodactylus kotschyi, and Tarentola mauritanica) and lacertids (Lacerta agilis, L. bilineata, Podarcis muralis, P. siculus, and Teira dugesii). Using serial and whole-mount histology, we found clear differences between gekkotans and lacertids in the structure of several cranial joints underlining the existence of two degrees of intracranial mobility. The lacertid species possess the anatomical features for streptostyly (quadrate joints) and metakinesis (parietal-supraoccipital and parabasisphenoid-pterygoid joints) and lack the anatomical correlates for mesokinesis (mobility of frontal-parietal and palatine-pterygoid joints) and amphikinesis (coupled mesokinesis, metakinesis, and streptostyly). In contrast, geckos present all the anatomical correlates for amphikinesis as described by the traditional quadratic crank model. Finally, we present a comprehensive summary of the different forms of squamate cranial kinesis, advancing two alternative hypotheses about the evolutionary origin of amphikinesis. Anat Rec, 297:463-472, 2014. V C 2013 Wiley Periodicals, Inc.

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“…; Moazen et al. ; Gussekloo et al. ), but it also has great potential in the simulation of growth and development of the craniofacial system.…”

Section: Introductionmentioning

confidence: 99%

“…The finite element (FE) method is a computational modelling technique that has been widely used to understand general craniofacial biomechanics (e.g. Ross et al 2005;Rayfield, 2007;Curtis et al 2011;Cox et al 2012;Moazen et al 2013;Gussekloo et al 2017), but it also has great potential in the simulation of growth and development of the craniofacial system. It can be used to predict the calvarial growth and to optimize reconstruction of various forms of craniosynostosis (Li et al 2013;Wolanski et al 2013;Libby et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Predicting calvarial growth in normal and craniosynostotic mice using a computational approach

et al. 2017

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During postnatal calvarial growth the brain grows gradually and the overlying bones and sutures accommodate that growth until the later juvenile stages. The whole process is coordinated through a complex series of biological, chemical and perhaps mechanical signals between various elements of the craniofacial system. The aim of this study was to investigate to what extent a computational model can accurately predict the calvarial growth in wild-type (WT) and mutant type (MT) Fgfr2 mice displaying bicoronal suture fusion. A series of morphological studies were carried out to quantify the calvarial growth at P3, P10 and P20 in both mouse types. MicroCT images of a P3 specimen were used to develop a finite element model of skull growth to predict the calvarial shape of WT and MT mice at P10. Sensitivity tests were performed and the results compared with ex vivo P10 data. Although the models were sensitive to the choice of input parameters, they predicted the overall skull growth in the WT and MT mice. The models also captured the difference between the ex vivoWT and MT mice. This modelling approach has the potential to be translated to human skull growth and to enhance our understanding of the different reconstruction methods used to manage clinically the different forms of craniosynostosis, and in the long term possibly reduce the number of re-operations in children displaying this condition and thereby enhance their quality of life.

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A Sensitivity Analysis to the Role of the Fronto‐Parietal Suture in Lacerta Bilineata: A Preliminary Finite Element Study

Cited by 15 publications

References 62 publications

Cranial sutures work collectively to distribute strain throughout the reptile skull

Cranial sutures work collectively to distribute strain throughout the reptile skull

To Move or Not to Move: Cranial Joints in European Gekkotans and Lacertids, an Osteological and Histological Perspective

Predicting calvarial growth in normal and craniosynostotic mice using a computational approach

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