A sensitive turn-on fluorescent probe for intracellular imaging of glutathione using single-layer MnO₂ nanosheet-quenched fluorescent carbon quantum dots

Abstract

A sensitive turn-on fluorescent sensor based on single-layer MnO2 nanosheet-quenched fluorescent carbon quantum dots has been developed for rapid and selective sensing of glutathione in aqueous solutions, as well as in living cells.

Glutathione‐Activatable and O2/Mn2+‐Evolving Nanocomposite for Highly Efficient and Selective Photodynamic and Gene‐Silencing Dual Therapy

“…In this regard, few studies have attempted to address the lack of stable and efficient PDT system integrated with GSH‐depleted agents . Recent reports have indicated that MnO 2 material can serve as an efficient GSH‐depleted agent to reduce GSH level . The PDT system with MnO 2 can hopefully overcome the overexpression of GSH in PDT process .…”

Graphene and graphene-like two-denominational materials based fluorescence resonance energy transfer (FRET) assays for biological applications

“…4). The limit of detection was reported to be 10 nM for GSH detection (He et al, 2015). Wang et al also reported a fluorescent glutathione probe based on MnO 2 and fluorescent phenol formaldehyde resin (PFR) nanocomposite (Wang et al, 2016).…”

Improving Functional Behavior of MCM‐41 by Encapsulating MnO2 Nanorods towards Simultaneous Determination of Purine Bases in DNA Samples

“…The -OH stretching vibration of the silanol group and adsorbed water molecules generate broad peak around 3400 cm À1 [11]. The peaks in the range 500-600 cm À1 in the FT-IR spectrum of MnO 2 (Figure 1Ab) are attributed to the MnÀO and MnÀOÀMn stretching vibrations [28,29]. FT-IR spectrum of the nanocomposite, MnO 2 @MCM-41 ( Figure 1Ac) possesses main absorption peaks of both MCM-41 and MnO 2 with slight changes.…”