A sensitive tapered-fiber optic biosensor for the label-free detection of organophosphate pesticides

Arjmand, Mojtaba; Saghafifar, Hossein; Alijanianzadeh, Mahdi; Soltanolkotabi, M.

doi:10.1016/j.snb.2017.04.121

Cited by 76 publications

(30 citation statements)

References 54 publications

(71 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This form of fiber facilitates better evanescent field interaction, providing greater sensitivity and specificity. A 2.4 × 10 −10 M limit for detecting methyl-parathion (a prohibited organophosphate due to its high toxicity indices for human health and the environment) makes these devices extremely useful for determining pesticide concentrations worldwide, which have caused intoxication and death in animals, plants, and human beings [136].…”

Section: Fibre-optic Biosensorsmentioning

confidence: 99%

Optical Biosensors for Therapeutic Drug Monitoring

et al. 2019

View full text Add to dashboard Cite

Therapeutic drug monitoring (TDM) is a fundamental tool when administering drugs that have a limited dosage or high toxicity, which could endanger the lives of patients. To carry out this monitoring, one can use different biological fluids, including blood, plasma, serum, and urine, among others. The help of specialized methodologies for TDM will allow for the pharmacodynamic and pharmacokinetic analysis of drugs and help adjust the dose before or during their administration. Techniques that are more versatile and label free for the rapid quantification of drugs employ biosensors, devices that consist of one element for biological recognition coupled to a signal transducer. Among biosensors are those of the optical biosensor type, which have been used for the quantification of different molecules of clinical interest, such as antibiotics, anticonvulsants, anti-cancer drugs, and heart failure. This review presents an overview of TDM at the global level considering various aspects and clinical applications. In addition, we review the contributions of optical biosensors to TDM.

show abstract

Section: Fibre-optic Biosensorsmentioning

confidence: 99%

Optical Biosensors for Therapeutic Drug Monitoring

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Optical fibers offer several advantages for field-portable and low-power qPCR given their inherent multiplexing capability, small size, and the vast array of portable fiber-integrated components that have arisen due to the telecommunications industry. This has already been proven in fields ranging from large scale structural health monitoring [ 32 , 33 ] through to biomedical applications [ [34] , [35] , [36] , [37] , [38] , [39] ]. Several optical fiber sensing schemes have been demonstrated for the detection of single-stranded DNA (ssDNA).…”

Section: Introductionmentioning

confidence: 99%

All-fiber all-optical quantitative polymerase chain reaction (qPCR)

Nguyen

Hill

et al. 2020

Sensors and Actuators B: Chemical

View full text Add to dashboard Cite

Highlights Quantitative polymerase chain reaction (qPCR) in an all-fiber all-optical configuration. Thermal cycling and fluorescence detection in a single optical-fiber-integrated device. Advantages of small sample volume, portability and high-speed operation. Potential ability to operate fluorescence-free through direct measurement of refractive index. Target application is disease and pathogen detection in remote communities.

show abstract

“…Sensors of chemicals and biosensors are designed to operate on the basis of several different phenomena, including electrochemical [10,11], optical [12][13][14], piezoelectric [15], gravimetric [16], and pyroelectric [17]. Our focus here lies on optical sensors, of which several types exist [18,19].…”

Section: Introductionmentioning

confidence: 99%

Artificial neural network to estimate the refractive index of a liquid infiltrating a chiral sculptured thin film

2019

View full text Add to dashboard Cite

We theoretically expanded the capabilities of optical sensing based on surface plasmon resonance in a prism-coupled configuration by incorporating artificial neural networks (ANNs). We used calculations modeling the situation in which an index-matched substrate with a metal thin film and a porous chiral sculptured thin film (CSTF) deposited successively on it is affixed to the base of a triangular prism. When a fluid is brought in contact with the exposed face of the CSTF, the latter is infiltrated. As a result of infiltration, the traversal of light entering one slanted face of the prism and exiting the other slanted face of the prism is affected. We trained two ANNs with differing structures using reflectance data generated from simulations to predict the refractive index of the infiltrant fluid. The best predictions were a result of training the ANN with simpler structure. With realistic simulated-noise, the performance of this ANN is robust.

show abstract

A sensitive tapered-fiber optic biosensor for the label-free detection of organophosphate pesticides

Cited by 76 publications

References 54 publications

Optical Biosensors for Therapeutic Drug Monitoring

Optical Biosensors for Therapeutic Drug Monitoring

All-fiber all-optical quantitative polymerase chain reaction (qPCR)

Artificial neural network to estimate the refractive index of a liquid infiltrating a chiral sculptured thin film

Contact Info

Product

Resources

About