Abstract:BackgroundHigh-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experimental and statistical issues that have yet to be addressed, and that will carry over to new high-throughput technologies unless they are investigated. One of the largest of these challenges is the selection of functionally consistent proteins.ResultsWe present a novel semi-nonparametric mixture model for classifying proteins as consiste… Show more
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