At present, the non-intrusive load decomposition method for low-frequency sampling data is as yet insufficient within the context of generalization performance, failing to meet the decomposition accuracy requirements when applied to novel scenarios. To address this issue, a non-intrusive load decomposition method based on instance-batch normalization network is proposed. This method uses an encoder-decoder structure with attention mechanism, in which skip connections are introduced at the corresponding layers of the encoder and decoder. In this way, the decoder can reconstruct a more accurate power sequence of the target. The proposed model was tested on two public datasets, REDD and UKDALE, and the performance was compared with mainstream algorithms. The results show that the F1 score was higher by an average of 18.4 when compared with mainstream algorithms. Additionally, the mean absolute error reduced by an average of 25%, and the root mean square error was reduced by an average of 22%.