A self-healable fluorescence active hydrogel based on ionic block copolymers prepared via ring opening polymerization and xanthate mediated RAFT polymerization

Abstract

In this work we report a facile method to prepare a fluorescence active self-healable hydrogel via the incorporation of fluorescence responsive ionic block copolymers (BCPs).

A self-healable and antifouling hydrogel based on PDMS centered ABA tri-block copolymer polymersomes: a potential material for therapeutic contact lenses

“…Synthesis of the tri-block copolymer of poly(N- [3-(dimethylamino)propyl]methacrylamide) (PDMAPM-b-PDMS-b-PDMAPM) using RAFT-PDMS-RAFT as a macro-RAFT reagent. In a typical xanthate mediated RAFT polymerization process, [30][31][32][33][34] PDMS macro RAFT (M n/GPC = 6000 g mol À1 ) (0.98 g, 1.63 Â 10 À4 mol) was dissolved in 1.5 ml of DMF in a Schlenk tube under inert (N 2 atm) conditions. After that, the monomer DMAPM (4.2 g, 2.4 Â 10 À2 mol) and a DMF solution of the thermal initiator ABCVA (0.012 g, 4.28 Â 10 À5 mol) (0.5 ml) were purged into the Schlenk tube (Table 1).…”

“…In this case, we have studied the self-healing characteristics of the hydrogel after the generation of artificial micro cracks. There have been several approaches to prepare self-healable polymer materials, such as based on Diels-Alder reactions, 26,27 disulfide reactions, 28,29 ionic interactions 30 etc.…”

Detecting and Monitoring Hydrogels with Medical Imaging

“…Another strategy for hydrogel visualization in vivo is the chemical grafting of contrast agents to the hydrogel via a covalent bond. ,,,− The chemical grafting of contrast agents has potential for monitoring both the hydrogel degradation and elimination route, which is valuable for biodegradable hydrogels. One of the factors that is critically important for monitoring hydrogels in vivo is the longevity of the contrast generation from the hydrogels.…”

Self‐Healable Hydrophobic Material Based on Anthracenyl Functionalized Fluorous Block Copolymers via Reversible Addition‐Fragmentation Chain Transfer Polymerization and Rapid Diels–Alder Reaction

“…[ 10,11 ] Unlike the extrinsic healing approach, intrinsic healing is based on reversible covalent bonds, [ 12–16 ] non‐covalent interactions, [ 17,18 ] or host‐guest interactions. [ 19–21 ] This can be inherently achieved multiple times via varied chemical or physical interactions, without any additives. Among the different chemical approaches, dynamic Diels–Alder (DA) chemistry, especially based on furan‐maleimide cycloaddition, [ 22,23 ] has attracted significant attention due to its straightforward and orthogonal selectivity, high conversion, and excellent yields without any byproduct formation.…”