A selenide linker for “traceless” solid-phase organic synthesis

Li, Zhengong; Kulkarni, B. A.; Ganesan, A.

doi:10.1002/1097-0290(2000)71:2<104::aid-bit1000>3.0.co;2-7

Cited by 7 publications

(1 citation statement)

References 23 publications

(18 reference statements)

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“…Plasma zinc was analysed by flame atomic absorption spectrophotometry (ContrAA 700, Analytik Jena, Germany [Smith, Butrimovitz, & Purdy, ]; interassay pooled serum CV = 4.2%), plasma selenium by microwave digestion (MarsXpress, CEM Corporation, North Carolina) followed by hydride generation atomic absorption spectrophotometry (ContrAA 700, Analytik Jena, Germany; interassay pooled serum CV = 6.2%) using a modified method of Li, Kulkarni, and Ganesan (). Accuracy for plasma zinc and selenium was established using certified reference materials.…”

Section: Participants and Methodsmentioning

confidence: 99%

Micronutrient status differs among Maasai and Kamba preschoolers in a supplementary feeding programme in Kenya

Houghton

Brown

Beaumont

et al. 2019

Maternal & Child Nutrition

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Since 2001, ChildFund Kenya has supplied micronutrient fortified school meals to preschoolers from two tribes (Kamba and Maasai) attending early childhood development (ECD) centres in Emali, S.E. Kenya. Lack of information on the micronutrient status of the preschoolers prompted a cross-sectional assessment of micronutrient (iron, zinc, selenium, vitamin A, vitamin D) status and prevalence of deficiencies among the two tribes. Data on sociodemographic, health, anthropometric status, and micronutrient supply from preschool meals were collected from 287 Kamba and 213 Maasai children aged 3 to 5 years attending 23 ECD centres. Nonfasting blood samples were collected for haemoglobin and plasma biomarkers of iron, zinc, selenium, vitamin A, vitamin D, C-reactive protein (CRP), α 1 -acid glycoprotein, and immunoglobin G. The prevalence of anaemia was significantly higher in Maasai children than Kamba (38%, 95% CI [31%, 45%], vs. 5%, [3%, 9%]), as well as iron deficiency and its various stages (P < 0.001). No differences were seen in the prevalence of zinc, selenium, vitamin A, or vitamin D deficiencies (all P > 0.05). Body iron, CRP, and age were significant predictors of haemoglobin concentrations for both tribes (all P < 0.006) and plasma 25-OHD for Maasai children only. The higher prevalence of iron deficiency among Maasai than Kamba children was possibly attributed to the high consumption of cow's milk (low in bioavailable iron) in place of micronutrient fortified meals together with a higher prevalence of chronic inflammation and intestinal damage.

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Section: Participants and Methodsmentioning

confidence: 99%

Micronutrient status differs among Maasai and Kamba preschoolers in a supplementary feeding programme in Kenya

Houghton

Brown

Beaumont

et al. 2019

Maternal & Child Nutrition

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Advances in Free Radical Reactions of Organoselenium and Organotellurium Compounds

Press

Back²

2011

Patai's Chemistry of Functional Groups

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Free radical reactions of organoselenium and tellurium compounds have been widely studied and exploited since the first two volumes of this series appeared. Alkyl aryl selenides and tellurides undergo alkyl C‐Se or C‐Te cleavage with stannanes or silanes to generate alkyl radicals that can be employed in reductions, allylations and both intermolecular and intramolecular additions to a large variety of unsaturated substrates, terminated by either hydrogen or arylchalcogen transfer. Selenoesters, telluroesters and related species generate acyl radicals that are useful in overall decarboxylations of carboxylic acids, and in addition and radical cyclization processes, including cascade reactions of polyenes to afford polycyclic products. Homolytic cleavage of diselenides and ditellurides produces selenyl and telluryl radicals that can be employed in additions to unsaturated acceptors, while the dichalcogenides themselves function as effective trapping agents for radicals produced in a variety of other ways, as from Barton thiohydroxamates. Selenols are efficient hydrogen donors that are of importance in kinetic studies of radical processes. When selenium and tellurium are joined to other heteroatoms, the resulting reagents effect radical 1,2‐additions to unsaturated substrates, as in the case of selenosulfonation and azidoselenenylation reactions. Other radical processes include oxidations, S H 2 substitutions, single electron transfers, extrusions and fragmentations, and reactions performed on solid supports. The synthetic utility of these processes, as well as mechanistic considerations are covered in this chapter.

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Selenium‐ and Tellurium‐Based Linker Units

Toy¹

2009

Linker Strategies in Solid‐Phase Organic Synthesis

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A selenide linker for “traceless” solid-phase organic synthesis

Cited by 7 publications

References 23 publications

Micronutrient status differs among Maasai and Kamba preschoolers in a supplementary feeding programme in Kenya

Micronutrient status differs among Maasai and Kamba preschoolers in a supplementary feeding programme in Kenya

Advances in Free Radical Reactions of Organoselenium and Organotellurium Compounds

Selenium‐ and Tellurium‐Based Linker Units

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