A selective dual-response biosensor for tyrosinase monophenolase activity based on lanthanide metal-organic frameworks assisted boric acid-levodopa polymer dots

An Overview of the Design of Metal-Organic Frameworks-Based Fluorescent Chemosensors and Biosensors

“…Enzymatic products can further react with other reagents to in-situ form complexes that can change the fluorescence of MOFs. Yu et al reported a dual-response biosensor, the detection of tyrosinase (TYR) monophenolase activity by integration of fluorescent polymer dots and luminescent lanthanide MOF (Ln-MOF) ( Figure 14 C) [ 189 ]. In this study, monoaromatic ligand DPA was used as the linker for the preparation of Eu 3+ -based Ln-MOF.…”

“…( C ) Schematic illustration of fluorescence on/off dual-response sensing of TYR monophenolase activity based on Eu-MOF-assisted boric acid-levodopa polymer dots. Reproduced with permission [ 189 ]. Copyright 2022, Elsevier.…”

Controllable Synthesis of TbIII Metal–Organic Frameworks with Reversible Luminescence Sensing for Benzaldehyde Vapor

“…Rare-earth-based optical materials with a large Stokes shift, high color purity, and strong luminescence properties have been widely used in optical devices, communication, sensing, and bioimaging. − Among them, lanthanide metal–organic frameworks (Ln-MOFs) have attracted great interest in the field of chemical sensing due to the tailorable luminescence properties and diverse energy-transfer processes derived from their editable components (organic ligands and metal ions/clusters). − Fluorescent signal changes in the sensing process gave high sensitivity and visualization to Ln-MOFs. − Up to now, Ln-MOFs have been used to detect heavy-metal ions or anions, nitroaromatic explosives, volatile organic compounds (VOCs), biomarkers, etc. − Shi’s group synthesized the novel {[Eu 2 (L) 3 (DMF) 2 ]·DMF·MeOH} n (Ln-MOF 1 ; H 2 L = 5-(4 H -1,2,4-triazol-4-yl)­benzene-1,3-dicarboxylic acid, DMF = N , N -dimethylformamide, and MeOH = methanol), which shows the red luminescence characteristic of Eu III . There is a competitive absorption between polychlorinated benzenes and Ln-MOF 1 , which prevents the “antenna effect”.…”

Rational design of a functionalized metal–organic framework for ratiometric fluorimetric sensing of Hg2+ in environmental water

“…[25][26][27] Therefore, the luminescence performance of Ln-MOF can be effectively regulated by rational design of the interaction between the ligand and metal ions. 28,29 Besides, the special ligand-metal energy transfer, namely the antenna effect (AE), can signicantly enhance the luminescence efficiency of lanthanide ions. 30,31 In this work, a functionalized Ln-MOF ratiometric uorimetric probe with dual uorescence emission signals was formed, which not only provided a built-in calibration reference by the uorescence of ligands, but also showed good quantitative ability based on the uorescence of lanthanide ions.…”