A selective dual quenching sensor (EY/BG@CDs) for simultaneous monitoring of gentamicin and ketorolac levels in plasma: a highly efficient platform that caters to the needs of therapeutic drug monitoring

Abstract

This research work introduces a novel sensor that utilizes two fluorophores to enable simultaneous monitoring of gentamicin sulphate (GNT) and ketorolac tromethamine (KET).

Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe

“…Finally the peaks at 880 cm −1 and 781 cm −1 correspond to out-of-plane C–H bending of aromatics, further confirming the presence of aromatic groups. 60 The FTIR spectrum suggests the N-CDs contain hydroxyl, carbonyl, carboxyl, amine/amide, aromatic, and aliphatic functional groups.…”

Cobalt-modulated dual emission carbon dots for ratiometric fluorescent vancomycin detection

“…The peak at 1633 cm −1 is attributed to C O stretching vibrations. 41 The peak at 1160 cm −1 corresponds to C–O stretching vibrations. The peak at 998 cm −1 indicates the presence of C–N stretching vibrations, possibly associated with amines.…”

Dual modulation of blue-fluorescent carbon dots for simultaneous detection of topotecan and pantoprazole

“…To understand how efficiently PNT quenches the emission of B@NCDs, the Stern–Volmer equation, F 0 / F = K sv [ Q ] + 1, was applied. 31 In this equation, F 0 is the fluorescence of B@NCDs without PNT, F is the fluorescence with PNT, K sv is a constant that measures quenching efficiency, and [ Q ] is the concentration of PNT. It's noted that with static quenching, K sv decreases as temperature goes up, but with dynamic quenching, K sv rises with increasing temperature.…”

“…29,30 This method presents several advantages, including its simplicity, cost-effectiveness, and the capability to precisely control the size and surface properties of the prepared carbon dots. 31–33 It also facilitates the production of carbon dots with enhanced fluorescence, making it a popular choice for synthesizing these versatile nanomaterials. 34,35…”