A Selective Advantage to Immigrant Genes in a
            <i>Daphnia</i>
            Metapopulation

Ebert, Dieter; Haag, Christoph R.; Kirkpatrick, Mark; Riek, Myriam; Hottinger, Jürgen W.; Pajunen, V. Ilmari

doi:10.1126/science.1067485

Cited by 224 publications

(279 citation statements)

References 35 publications

Supporting

Mentioning

266

Contrasting

Order By: Relevance

“…Furthermore, in one of the species, hybrid vigour after immigration was confirmed experimentally (Ebert et al, 2002). In the present study, we carried out a detailed analysis of the spatial structure of genetic variation in these two metapopulations, because the geographic scale at which migration takes place may influence both genetic drift during colonization and selection for immigrant genes due to hybrid vigour.…”

Section: Introductionmentioning

confidence: 83%

“…Another important consequence of founder events is local inbreeding ('drift load'), which in some situations leads to hybrid vigour after immigration ('genetic rescue effect'; Whitlock et al, 2000;Ebert et al, 2002;Saccheri and Brakefield, 2002). Hybrid vigour increases effective migration rate because it confers a selective advantage to immigrant genes Ebert et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

“…Hybrid vigour increases effective migration rate because it confers a selective advantage to immigrant genes Ebert et al, 2002). This process, in combination with increased drift during colonization, may contribute to a genetic population structure, in which young populations have a lower local genetic diversity and are more differentiated from each other than older populations (Whitlock, 1992a;McCauley et al, 1995;Nurnberger and Harrison, 1995;Giles and Goudet, 1997;Roach et al, 2001;Haag et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations

et al. 2005

View full text Add to dashboard Cite

The genetic structure of metapopulations offers insights into the genetic consequences of local extinction and recolonization. We studied allozyme variation in rock pool metapopulations of two species of waterfleas (Daphnia) with the aim to understand how these dynamics influence genetic differentiation. We screened 138 populations of D. magna and 65 populations of D. longispina from an area in the archipelago of southern Finland. The pools from which they were sampled are separated by distances between 1.5 and 4710 m and located on a total of 38 islands. The genetic population structure of the two species was strikingly similar, consistent with their similar metapopulation ecology. The mean F PT value (differentiation among pools with respect to the total metapopulation) was 0.55 and a hierarchical analysis showed that genetic differentiation was strong (40.25) among pools within islands as well as among whole islands. Within islands, pairwise genetic differentiation increased with geographic distance, indicating isolation by distance due to spatially limited dispersal. Previous studies have shown strong founder events occurring during colonization in our metapopulation. We suggest that the genetic population structure in the studied metapopulations is largely explained by three consequences of these founder events: (i) strong drift during colonization, (ii) local inbreeding, which results in hybrid vigour and increased effective migration rates after subsequent immigration, and (iii) effects of selection through hitchhiking of neutral genes with linked loci under selection.

show abstract

Section: Introductionmentioning

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations

et al. 2005

View full text Add to dashboard Cite

show abstract

“…To what extent these potential fitness costs of genetic rescue are larger than the fitness benefits is, therefore, an important issue in conservation genetics. Second, when the immigrants are successful their genomes can increase rapidly and disproportional in frequency in the recipient population in a few generations (Ball et al 2000;Ebert et al 2002;Saccheri and Brakefield 2002). As such, the immigrant genomes become overrepresented in the rescued population thereby reducing the genetically effective population size, N e , rather than increasing it (Hedrick and Fredrickson 2010).…”

Section: Introductionmentioning

confidence: 99%

Dynamics of genetic rescue in inbred Drosophila melanogaster populations

et al. 2010

View full text Add to dashboard Cite

Genetic rescue has been proposed as a management strategy to improve the fitness of genetically eroded populations by alleviating inbreeding depression. We studied the dynamics of genetic rescue in inbred populations of Drosophila. Using balancer chromosomes, we show that the force of heterosis that accompanies genetic rescue is large and allows even a recessive lethal to increase substantially in frequency in the rescued populations, particularly at stress temperatures. This indicates that deleterious alleles present in the immigrants can increase significantly in frequency in the recipient population when they are in linkage disequilibrium with genes responsible for the heterosis. In a second experiment we rescued eight inbred Drosophila populations with immigrants from two other inbred populations and observe: (i) there is a significant increase in viability both 5 and 10 generations after the rescue event, showing that the increase in fitness is not transient but persists long-term. (ii) The lower the fitness of the recipient population the larger the fitness increase. (iii) The increase in fitness depends significantly on the origin of the rescuers. The immigrants used were fixed for a conditional lethal that was mildly deleterious at 25°C but lethal at 29°C. By comparing fitness at 25°C (the temperature during the rescue experiment) and 29°C, we show that the lethal allele reached significant frequencies in most rescued populations, which upon renewed inbreeding became fixed in part of the inbred lines. In conclusion, in addition to the fitness increase genetic rescue can easily result in a substantial increase in the frequency of mildly deleterious alleles carried by the immigrants. This can endanger the rescued population greatly when it undergoes recurrent inbreeding. However, using a sufficient number of immigrants and to accompany the rescue event with the right demographic measures will overcome this problem. As such, genetic rescue still is a viable option to manage genetically eroded populations.

show abstract

“…Gene flow, in the form of effective individual gene movement within and between populations, is one of the most important factors for maintaining genetic diversity within a species and counteracting the negative effects of habitat fragmentation [1,2]. Landscape connectivity [3,4], based on landscape features, is critical for the persistence of spatially structured populations.…”

Section: Introductionmentioning

confidence: 99%

Landscape features influence gene flow as measured by cost-distance and genetic analyses: a case study for giant pandas in the Daxiangling and Xiaoxiangling Mountains

et al. 2010

View full text Add to dashboard Cite

BackgroundGene flow maintains genetic diversity within a species and is influenced by individual behavior and the geographical features of the species' habitat. Here, we have characterized the geographical distribution of genetic patterns in giant pandas (Ailuropoda melanoleuca) living in four isolated patches of the Xiaoxiangling and Daxiangling Mountains. Three geographic distance definitions were used with the "isolation by distance theory": Euclidean distance (EUD), least-cost path distance (LCD) defined by food resources, and LCD defined by habitat suitability.ResultsA total of 136 genotypes were obtained from 192 fecal samples and one blood sample, corresponding to 53 unique genotypes. Geographical maps plotted at high resolution using smaller neighborhood radius definitions produced large cost distances, because smaller radii include a finer level of detail in considering each pixel. Mantel tests showed that most correlation indices, particularly bamboo resources defined for different sizes of raster cell, were slightly larger than the correlations calculated for the Euclidean distance, with the exception of Patch C. We found that natural barriers might have decreased gene flow between the Xiaoxiangling and Daxiangling regions.ConclusionsLandscape features were found to partially influence gene flow in the giant panda population. This result is closely linked to the biological character and behavior of giant pandas because, as bamboo feeders, individuals spend most of their lives eating bamboo or moving within the bamboo forest. Landscape-based genetic analysis suggests that gene flow will be enhanced if the connectivity between currently fragmented bamboo forests is increased.

show abstract

A Selective Advantage to Immigrant Genes in a Daphnia Metapopulation

Cited by 224 publications

References 35 publications

Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations

Founder events as determinants of within-island and among-island genetic structure of Daphnia metapopulations

Dynamics of genetic rescue in inbred Drosophila melanogaster populations

Landscape features influence gene flow as measured by cost-distance and genetic analyses: a case study for giant pandas in the Daxiangling and Xiaoxiangling Mountains

Contact Info

Product

Resources

About