A pH‐ and redox‐stimulated responsive hollow mesoporous silica for triggered delivery of fungicides to control downy mildew of Luffa cylindrica

Abstract

BACKGROUND: Downy mildew, a devastating disease of cucurbitaceous crops caused by Pseudoperonospora cubensis. Although a variety of fungicides are used to control downy mildew, choosing an effective product can be challenging. Environmental stimulus-responsive pesticide delivery systems have great potential to improve the effectiveness of disease and pest control and reduce the impact on environmentally beneficial organisms. RESULTS: In this work, a disulfide bond (SS)-modified and chitosan oligosaccharide (COS)-capped hollow mesoporous silica (HMS) pesticide delivery system was synthesized using a hard template method for the control of downy mildew in cucurbit crops. The synthesized nanoparticles were loaded with dimethomorph (DMM)

Construction and biological effects of a redox‐enzyme dual‐responsive lufenuron nano‐controlled release formulation

“…On addition of cellulase, cellulose on the surface of Luf@MSNs‐ss‐cellulose is hydrolyzed, which opens the gateway and accelerates lufenuron release. On simultaneous addition of glutathione and cellulase, the cumulative release rate of Luf@MSNs‐ss‐cellulose reached a maximum, which was attributed to the hydrolysis of cellulose as a gateway and the redox reaction of disulfide bonds with glutathione, which destroyed the structure of Luf@MSNs‐ss‐cellulose 41,64 …”

“…Toxicity of Luf@EW and Luf@MSNs-ss-cellulose against Ostrinia furnacalis larvae at 0, 7 and 14 days after spraying wileyonlinelibrary.com/journal/ps maximum, which was attributed to the hydrolysis of cellulose as a gateway and the redox reaction of disulfide bonds with glutathione, which destroyed the structure of Luf@MSNs-ss-cellulose. 41,64 3.3 The degradation of Luf@MSNs-ss-cellulose The stimulatory effects of glutathione and cellulase on Luf@MSNsss-cellulose nanoparticles were studied. As shown in Fig.…”

Enhanced Insecticidal Activity of Chlorfenapyr against Spodoptera frugiperda by Reshaping the Intestinal Microbial Community and Interfering with the Metabolism of Iron-Based Metal–Organic Frameworks

“…Each of these solutions, which were taken 1 mL at 2, 4, 6, 8, 12, 24, 36, 48, 72, 96, and 120 h, was centrifuged at 15,000 rpm, and the supernatants were collected for HPLC analysis. The CF concentration released from the treatment was calculated using the following equation: Q t ( % ) = C t × V 1 + ∑ 0 t C t × V 2 × 100 M where Q t is the cumulative amount of CF released in time t (min), M is the actual amount of CF loaded in the 100 mg sample, C t is the measured concentration of CF at release time t (h), V 1 is the total volume of the test solution, and V 2 is the volume of the sample spirated at time t (h).…”

Porous Silica Nanocarriers: Advances in Structural Orientation and Modification to Develop Sustainable Pesticide Delivery Systems

“…The study found that in the presence of GSH, 62.64% of the pesticide was released after 15 days, while in its absence, only 19.06% of the pesticide was released. 143 The presence of a reducing agent, such as the sulfhydryl group found in glutathione, breaks the disulfide bond on the surface of the nanoparticles, causing the chitosan oligosaccharide (COS) to detach and release the pesticide rapidly. The reducing agent oxidizes itself in the process, turning into oxidized glutathione (GSSG) and reducing the disulfide bond to a sulfhydryl group.…”