A School-Based Study with Rome III Criteria on the Prevalence of Functional Gastrointestinal Disorders in Chinese College and University Students

Dong, Yanyan; Chen, Fei-Xue; Yu, Yanbo; Du, Chao; Qi, Qingqing; Han, Lu; Li, Yanqing

doi:10.1371/journal.pone.0054183

Cited by 64 publications

(61 citation statements)

References 44 publications

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“…The Chinese version has been widely used in China in recent years (Dong et al, 2013). The diagnosis of IBS was based on the presence of abdominal pain or discomfort for at least three months during the previous six months, with at least two or more of the following conditions: symptoms associated with a change in frequency or form of stool, pain improved after defecation.…”

Section: Chinese Version Of Rome III Questionnairementioning

confidence: 99%

“…The diagnosis of IBS was based on the presence of abdominal pain or discomfort for at least three months during the previous six months, with at least two or more of the following conditions: symptoms associated with a change in frequency or form of stool, pain improved after defecation. Patients with IBS were divided into diarrhea-predominant IBS (IBS-D), constipationpredominant IBS (IBS-C), mixed IBS (IBS-M), and un-subtyped IBS (IBS-U) according to the proportion of hard and lumpy stools (Dong et al, 2013).…”

Section: Chinese Version Of Rome III Questionnairementioning

confidence: 99%

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A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

Liu

Xiao

Yao

2014

J. Zhejiang Univ. Sci. B

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Abstract:The prevalence of irritable bowel syndrome (IBS) and associated factors, especially psychological and lifestyle factors, in nurses in China have not been investigated previously. The aims of this study were to assess the prevalence of IBS in nurses, to evaluate whether factors, such as psychological disorders, are associated with IBS, and to determine whether psychological disorders can influence the severity of symptoms of IBS and quality of life (QOL). A cross-sectional study was conducted for Chinese nurses from November 2012 to February 2013. Participants were asked to complete questionnaires. The prevalence of IBS was 17.4%. The revised symptom checklist 90 (SCL-90-R) scores were significantly higher for nurses with IBS than for those without IBS (P<0.001), and no difference in scores between IBS subtypes was found (F=1.893, P=0.142). The scores of QOL for nurses with and without IBS were 77.18±21.93 and 88.44±11.89 (P<0.001), respectively. Psychological disorders did not show statistically significant correlations with severity of symptoms of IBS or QOL. Alcohol consumption, low level of exercise, and psychological disorders were risk factors for IBS. In summary, nurses in China show a high prevalence of IBS. Psychological disorders and some related lifestyle factors are probably responsible for the development of IBS in nurses.

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Section: Chinese Version Of Rome III Questionnairementioning

confidence: 99%

Section: Chinese Version Of Rome III Questionnairementioning

confidence: 99%

A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

Liu

Xiao

Yao

2014

J. Zhejiang Univ. Sci. B

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“…A Mexican database based on the Rome II Modular Questionnaire showed that IBS accounted for 28.9% of patients whilst FD accounted for only 4.0% [13]. Even in East Asia, data from 4,638 Chinese college and university students revealed a similar prevalence between FD (9.25%) and IBS (8.34%) [14]. There is the possibility of recall bias amongst physicians, easier access to upper gastrointestinal endoscopy in East Asia than in Western and Latin countries, or oversight of the impact of overlapping IBS with FD [15] in the institutions in this study.…”

Section: Discussionmentioning

confidence: 99%

Survey of Clinical Practice for Irritable Bowel Syndrome in East Asian Countries

et al. 2015

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Aim: Sociocultural factors are important because their different effects on the features of irritable bowel syndrome (IBS) between countries will provide clues towards solving this problem. The aims of this study were to depict the clinical realities of IBS in East Asian countries and test the hypothesis that the diagnosis and treatment of IBS differ between countries. Subjects and Methods: Study participants were 251 physicians involved in the clinical practice of IBS at major institutions in Japan, South Korea, China, the Philippines, Indonesia and Singapore. The questionnaire contained 45 questions focused on the clinical practice of IBS. Results: Subjects in Japan, South Korea, China, Indonesia, the Philippines and Singapore accounted for 55.4, 17.9, 8.8, 8.0, 6.4 and 3.6% of the study cohort, respectively. Amongst East Asian physicians, the most important symptom was considered to be abdominal pain by 33.4%, whilst 24.3% regarded alternating diarrhea and constipation to be the most important symptoms. Total colonoscopy and histopathology use showed no difference among countries. Prescriptions given for mild (p < 0.0001), moderate (p < 0.0001), severe (p < 0.0001), intractable (p = 0.002), diarrheal (p < 0.0001) and constipating (p < 0.0001) patients with IBS significantly differed between the countries. Except for several minor points, IBS specialists showed no significant difference in their diagnosis and treatment of IBS when compared to nonspecialists. Conclusion: This survey provided data on the clinical treatment of IBS among East Asian countries. The results supported the hypothesis that the diagnosis and treatment of IBS differs between countries.

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“…1 shows the experimental process. HADS is commonly used for estimating emotional disorders, and can be divided into anxiety (HAD-A) and depression (HAD-D) subscales (Dong et al, 2013). For each subscale, there are seven questions.…”

Section: Participantsmentioning

confidence: 99%

Visceral and somatic hypersensitivity, autonomic cardiovascular dysfunction and low-grade inflammation in a subset of irritable bowel syndrome patients

Liu

Chen

et al. 2014

J. Zhejiang Univ. Sci. B

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Abstract:The pathophysiology of irritable bowel syndrome (IBS) is complex and not fully understood, so the aim of this study was to evaluate whether visceral and somatic hypersensitivity, autonomic cardiovascular dysfunction, and low-grade inflammation of the gut wall are associated with diarrhea-predominant IBS (D-IBS). Sixty-two patients with D-IBS and 20 control subjects participated in the study. Using the ascending method of limits (AML) protocol, we demonstrated that D-IBS patients had significantly lower sensory thresholds compared with healthy controls (P<0.001). Using diverse methods, especially the ischemic sensitivity test, for the first time in China, we confirmed that D-IBS patients have somatic hypersensitivity. They had a significantly higher systolic blood pressure and heart rate after a cold stimulus, indicative of autonomic cardiovascular dysfunction. Compared with the control group, D-IBS patients had a significantly higher level of calprotectin (P<0.001). We also found significant correlations between visceral and somatic hypersensitivity, visceral hypersensitivity and autonomic cardiovascular dysfunction, and somatic hypersensitivity and autonomic cardiovascular dysfunction. Our findings may provide valuable suggestions for the treatment of D-IBS.

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A School-Based Study with Rome III Criteria on the Prevalence of Functional Gastrointestinal Disorders in Chinese College and University Students

Cited by 64 publications

References 44 publications

A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

A cross-sectional study of irritable bowel syndrome in nurses in China: prevalence and associated psychological and lifestyle factors

Survey of Clinical Practice for Irritable Bowel Syndrome in East Asian Countries

Visceral and somatic hypersensitivity, autonomic cardiovascular dysfunction and low-grade inflammation in a subset of irritable bowel syndrome patients

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