A Schizophyllum commune fungus ball in a lung cancer cavity: a case report

Akazawa, Nana; Murakami, Hiromi; Ishibana, Yuichi; Takahashi, Yusuke; Hosoda, Waki; Yaguchi, Takashi; Kamei, Katsuhiko

doi:10.1186/s12879-021-06739-8

Cited by 9 publications

(5 citation statements)

References 22 publications

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“…Among the above discussed species, the species F. velutipes were characterized for HCs; the genus Malassezia was significantly abundant in the BP group; and genus Penicillium was significantly abundant in the LC group. Another species, Schizophyllum commune, which can cause respiratory system infections, was significantly enriched in the ILD group ( Itoh et al, 2021 ). The genus Pyrenophora was the character taxa in the FP group.…”

Section: Discussionmentioning

confidence: 99%

Upper respiratory tract mycobiome alterations in different kinds of pulmonary disease

Ding

et al. 2023

Front. Microbiol.

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IntroductionThe human respiratory tract is considered to be a polymicrobial niche, and an imbalance in the microorganism composition is normally associated with several respiratory diseases. In addition to the well-studied bacteriome, the existence of fungal species in the respiratory tract has drawn increasing attention and has been suggested to have a significant clinical impact. However, the understanding of the respiratory fungal microbiota (mycobiome) in pulmonary diseases is still insufficient.MethodsIn this study, we investigated the fungal community composition of oropharynx swab (OS) samples from patients with five kinds of pulmonary disease, including interstitial lung disease (ILD), bacterial pneumonia (BP), fungal pneumonia (FP), asthma (AS) and lung cancer (LC), and compared them with healthy controls (HCs), based on high-throughput sequencing of the amplified fungal internal transcribed spacer (ITS) region.ResultsThe results showed significant differences in fungal composition and abundance between disease groups and HCs. Malassezia was the most significant genus, which was much more abundant in pulmonary diseases than in the control. In addition, many common taxa were shared among different disease groups, but differences in taxa abundance and specific species in distinct disease groups were also observed. Based on linear discriminant analysis effect size (LefSe), each group had its characteristic species. Furthermore, some species showed a significant correlation with the patient clinical characteristics.DiscussionOur study deepened our understanding of the respiratory tract mycobiome in some diseases that are less studied and identified the commonalities and differences among different kinds of pulmonary disease. These results would provide the solid basis for further investigation of the association between the mycobiome and pathogenicity of pulmonary diseases.

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Section: Discussionmentioning

confidence: 99%

Upper respiratory tract mycobiome alterations in different kinds of pulmonary disease

Ding

et al. 2023

Front. Microbiol.

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“…Cases have reported that it can present with vascular and tissue invasion, as brain abscess and with pneumonia or as allergic bronchopulmonary mycosis in immunocompromised individuals. [6][7][8] Till date there is no single factor associated with S. commune infection, but it is mostly associated with young, male patients who are agricultural workers. In our patient, we noticed that it had occurred in an elderly female patient from an urban background.…”

Section: Discussionmentioning

confidence: 99%

Schizophyllum commune – A rare isolate from fungal sinusitis

Muthiah,

Murugesan

2023

IJMMTD

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is a basidiomycete that has been occasionally reported to cause sinusitis, allergic bronchopulmonary mycosis, and co-infection with allergic bronchopulmonary aspergillosis. Even though it is an environmental fungus, cases have been reported with vascular and tissue invasion and even presented as brain abscess in immunocompromised individuals. As there are reports of as an emerging fungal pathogen causing rhinosinusitis, laboratories should not ignore this as an environmental contaminant. Microbiologists must consider this as a possible pathogen and should report with clinical correlation. We present a case report of fungal sinus infection, as it is a rare occurrence and since we have noticed it for the first time in our hospital.

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“…During isolation of Saprolegnia species from the site of infection or water, some fungal contaminants may also be present. Some of the fungal species encountered were of Didymella, Phoma, Schizophyllum and Emmia which also produced white colonies [25] , [26] , [27] , [28] . Hence identification of Saprolegnia species based on culture morphology may be difficult for untrained eyes.…”

Section: Discussionmentioning

confidence: 99%