A safe in-home disposal system with every opioid prescription? Food and Drug Administration is considering a potential new Risk Evaluation and Mitigation Strategy that could impact pharmacists

Stubbings, JoAnn; Crawford, Stephanie Y.; Menighan, Thomas E.

doi:10.1016/j.japh.2021.11.009

Cited by 3 publications

(1 citation statement)

References 12 publications

(12 reference statements)

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“…Several states (not in our catchment area) have enacted laws requiring manufacturers to fund drug disposal. In 2020, the state of Washington launched their state‐wide drug take‐back program (which is funded by drug manufacturers) though no opioid‐specific disposal outcomes have been reported 62 . Finally, news media and the federal government have increased awareness of the opioid crisis and its associated risks 63,64 …”

Section: Discussionmentioning

confidence: 99%

Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Huang,

Bleicher,

Torre

et al. 2023

Health Services Research

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ObjectiveTo evaluate a health system‐wide intervention distributing free home‐disposal bags to surgery patients prescribed opioids.Data Sources and Study SettingWe collected patient surveys and electronic medical record data at an academic health system.Study DesignWe conducted a prospective observational study. The bags were primarily distributed at pharmacies, though pharmacists delivered bags to some patients. The primary outcome was disposal of leftover opioids (effectiveness). Secondary outcomes were patient willingness to dispose and factors associated with disposal (effectiveness), recalling receipt of the bag (reach), and recalling receipt of bags and disposal over time (maintenance). We used a modified Poisson regression to evaluate the relative risk of disposal. Inverse probability of treatment weighting, based on propensity scores, was used to account for differences between survey responders and non‐responders and reduce nonresponse bias.Data Collection/Extraction MethodsFrom August 2020 to May 2021, we surveyed patients 2 weeks after discharge (allowing for home opioid use). Eligibility criteria were age ≥18, English being primary language, valid email address, hospitalization ≤30 days, discharge home, and an opioid prescription sent to a system pharmacy.Principal FindingsWe identified 5134 patients with 2174 completing the survey (response rate 42.3%). Among respondents, 1375 (63.8%) recalled receiving the disposal bag. Among 1075 respondents with leftover opioids, 284 (26.4%) disposed, 552 (51.3%) planned to dispose, 79 (7.4%) did not plan to dispose, 69 (6.4%) had undecided, and 91 (8.5%) had not considered disposal. Recalling receipt of the bag (incidence rate ratio [IRR] 1.25, 95% confidence interval [CI] 1.13–1.37) was positively associated with disposal. Patients who used opioids in the last year were less likely to dispose (IRR 0.82, 95% CI 0.73–0.93). Disposal rates remained stable over the study period while recalling receipt of bags trended up.ConclusionsA pragmatic implementation of a disposal intervention resulted in lower disposal rates than prior trials.

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Section: Discussionmentioning

confidence: 99%

Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Huang,

Bleicher,

Torre

et al. 2023

Health Services Research

View full text Add to dashboard Cite

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Elucidating determinants of medication disposal programs at retail pharmacies in North Carolina

Egan,

McCallum,

Matthews

et al. 2024

Journal of the American Pharmacists Association

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Exploring the harm reduction paradigm: the role of Board-Certified Psychiatric Pharmacists

Douglass,

Maister,

Moeller

et al. 2024

Mental Health Clinician

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Deaths related to opioid overdoses continue to climb, and there remains a need for innovative strategies to address this ongoing crisis. Harm reduction (HR), a nonjudgmental philosophy aimed at reducing consequences associated with drug use and other potentially unsafe behavior, has emerged as a compassionate and effective approach. Harm reduction further emphasizes overdose prevention and fosters a shift in perspective that recognizes substance use disorder as a disease and not a moral failing. The tenets of HR collectively advocate for the well-being of individuals who use substances and support any positive change as defined by the individual. Given the high rate of morbidity and mortality associated with substance misuse and barriers or ambivalence to receiving treatment, awareness of and advocacy for HR practice is essential. This manuscript aims to describe evidence-based HR interventions, provide a foundation for the implementation of services, and further promote the importance of providing humanistic care without judgment. As valued members of the multidisciplinary treatment team, Board-Certified Psychiatric Pharmacists should implement and engage in HR services in the settings where people with substance use disorders receive care.

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A safe in-home disposal system with every opioid prescription? Food and Drug Administration is considering a potential new Risk Evaluation and Mitigation Strategy that could impact pharmacists

Cited by 3 publications

References 12 publications

Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Elucidating determinants of medication disposal programs at retail pharmacies in North Carolina

Exploring the harm reduction paradigm: the role of Board-Certified Psychiatric Pharmacists

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