A safe and novel method for video-assisted thoracic surgery preoperative localization of small pulmonary nodules by using ZT medical glue (2-octyl cyanoacrylate)

Wang, Bin; Zeng, Yong; Zhao, Zhenhua; Wang, Ting; Ma, Zhifeng; Yu, Guanzhen

doi:10.1016/j.suronc.2020.02.001

Cited by 17 publications

(18 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The widespread usage of the hook-wire localization technique benefits from its accurate localization, high success rate, simple operation, fewer complications, and no interference with pathological diagnosis. Alternatively, medical glue may be used for pre-operative localization of pulmonary nodules ( 11 ). Such medical glue is made of synthetic cyanoacrylate, which is non-toxic and safe.…”

Section: Discussionmentioning

confidence: 99%

“…The most common complications associated with localization procedures include pneumothorax and pulmonary parenchymal hemorrhage. The glue sets fast enough to effectively block the puncture site and reduce complications such as lung leak and bleeding ( 11 ). In the medical glue group, minor pneumothorax and mild pulmonary parenchymal hemorrhage occurred in 11.9% and 13.1% of patients, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Several methods have been reported for pre-operative localization of pulmonary nodules, including intraoperative ultrasound ( 7 , 8 ), hook-wire localization ( 9 , 10 ), medical glue ( 11 ), micro-coil ( 12 ), methylene blue ( 13 ), indocyanine green ( 14 ), or radionuclides ( 15 ), some with 100% localization success rate ( 16 ). Pneumothorax or parenchymal hemorrhage are common complications during pre-operative localization, while fatal consequences are rarely reported ( 17 , 18 ).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparison of hook-wire and medical glue for CT-guided preoperative localization of pulmonary nodules

et al. 2022

View full text Add to dashboard Cite

BackgroundPreoperative localization is challenging due to the small diameter of pulmonary nodules or their deep location in the lung parenchyma during VATS surgery. The purpose of this study was to compare the efficacy and safety of both hook-wire and medical glue for pre-operative localization of pulmonary nodules.MethodsIn the current study, 158 patients were retrospectively analyzed (January 2019 and January 2020). The patients underwent hook-wire or medical glue for pre-operative localization of pulmonary nodules. Among them, 74 patients in the hook-wire group and 84 patients in the medical glue group underwent VATS anatomic segmentectomy or wedge resection after localization of pulmonary nodules. Pre-operative localization data from all patients were compiled. Moreover, the efficacy and safety of the two methods were evaluated according to localization success rates and localization-related complications.ResultsThe success rate of localization in the medical glue group was 100% while 97.3% in the hook-wire group. After localization of the pulmonary nodules, the incidence of minor pneumothorax in the medical glue group (11.9%) was lower than that in the hook-wire group (37.8%) (p=0.01). The incidence of mild pulmonary parenchymal hemorrhage in the medical glue group (13.1%) was also lower than that in the hook-wire group (24.3%) (p=0.000). The mean time from the completion of localization to the start of surgery was also longer in the medical glue group than in the hook-wire group (p=0.000). The mean visual analog scale (VAS) scores after localization were higher in the hook-wire group than in the medical glue group (p=0.02). In both groups, parenchymal hemorrhage was significantly associated with the needle length in hook-wire localization and the depth of the medical glue in the lung parenchyma (p = 0.009 and 0.001, respectively).ConclusionThese two localization methods are safe and effective in pre-operative pulmonary nodule localization. The medical glue localization method had a lower risk of complications, a higher localization success rate, less pain after localization and more flexibility in the arrangement of operation time.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of hook-wire and medical glue for CT-guided preoperative localization of pulmonary nodules

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Both solid and liquid materials, such as hookwires, 9‐14 lipiodol, 15 microcoils, 12,16,17 dye 17,18 and radiotracers 19 have been developed as localization markers. We summarized the literature on preoperative localization techniques with sample numbers >100 and other similar studies published within the last five years, 11,20‐25 and compared the results with ours (Table 4 ) . Although these methods have been applied widely in clinical practice and reported favorable results, they reveal some shortcomings.…”

Section: Discussionmentioning

confidence: 99%

A novel technique for preoperative localization of pulmonary nodules using a mixture of tissue adhesive and iohexol under computed tomography guidance: A 140 patient single‐center study

Zhang

Peng

et al. 2021

Thoracic Cancer

View full text Add to dashboard Cite

Background The increase in the incidence of pulmonary nodules has made computed tomography (CT) screening a requirement for diagnosis and treatment. Small pulmonary nodule detection during video‐assisted thoracoscopic surgery (VATS) or thoracotomy is frequently challenging; however, accurate and efficient localization of nodules is critical for precise resection. Herein, we introduce and evaluate the feasibility and safety of a novel technique for preoperative pulmonary nodule localization. Methods From March 2018 to December 2019, 140 patients with 153 pulmonary nodules measuring <2 cm in diameter were enrolled in this study. Preoperative, CT‐guided localization was performed on each nodule with an injected mixture of tissue adhesive and iohexol. Patient and nodule characteristics, localization data, complications, surgical data, and pathological results were analyzed. Results All 153 nodules in 140 patients were successfully marked preoperatively and detected during surgery (n = 153/153). Mean nodule size was 8.7 ± 2.6 mm, and mean distance from nodule to pleura was 7.9 ± 8.2 mm. The mean procedural time was 8.7 ± 1.0 min. Nine patients (6.4%) underwent two simultaneous nodule localizations and two patients (1.4%) underwent three simultaneous nodule localizations. Pneumothorax (17/140, 12.1%), pain (6/140, 4.3%), and pungent odor (5/140, 3.6%) were the major complications. No patient required further treatment, and no allergic reactions or embolisms were observed. Conclusions Preoperative CT‐guided nodule localization using a mixture of tissue adhesive and iohexol is an efficient technique for localizing small and impalpable pulmonary lesions, including multiple pulmonary nodules. Our study demonstrates that this novel method is safe and straightforward to implement.

show abstract

“…Imaging positioning methods include intraoperative ultrasonic positioning [19], near-infrared uorescence imaging positioning [20] and surgical navigation puncture robot system [21], but the requirements for equipment and the technical level of operators were high, which was di cult to be widely popularized. However, injection of liquid material-mediated localization method, including injection of lipiodol [22], methylene blue [23], medical glue [24], indocyanine green uorescent agent [25] and other liquids, had some shortcomings such as short retention time, easy diffusion and uncontrollable injection dose, and had not received more attention from thoracic surgeons.…”

Section: Comparison Of Vats Operation Indexes Between the Two Groupsmentioning

confidence: 99%

CT Guided Placement of the End of the Microcoil in the Pleural Cavity: A More Helpful Method for Video-Assisted Thoracic Surgery (VATS) Resection of Ground Glass Opacity (GGO)

Dong

et al. 2021

Preprint

View full text Add to dashboard Cite

Objective To investigate and summarize the effectiveness and safety of CT guided microcoil localization before video-assisted thoracic surgery (VATS) for the removal of ground glass opacity (GGO).Method 147 patients with GGO who were treated in our hospital from January 2019 to February 2021 were retrospectively analyzed. They were divided into two groups according to the final position of the end of the microcoil, intracavity group (n=78) and extracavity group (n=69). Comparison of the two groups of patients with puncture complications, and the influence of the end position of the coil for VATS.Results The proportion of supine and prone position in the intracavity group was significantly higher than that in the extracavity group (82.1% vs. 66.7%, P<0.05). The incidence of intrapulmonary hemorrhage, chest pain and coil displacement in the intracavitary group was significantly lower than that in the extracavitary group (28.2% vs. 46.4%; 19.2% vs. 39.1%;1.3% vs. 11.6%, P<0.05), and the incidence of pneumothorax had no significant difference(P>0.05). The time of VATS and the rate of conversion to thoracotomy in the intracavity group were significantly lower than those in the extracavity group (103.4±21.0min vs. 112.2±17.3min, 0% vs. 5.8%, P<0.05).Conclusion CT-guided placement of the microcoil was a very practical, simple and convenient localization method before VATS with high success rate and few complications, further more, it was a better method to place the end of the coil in the pleural cavity because of the lower complication rate, shorter VATS time and lower rate of thoracotomy conversion.

show abstract

A safe and novel method for video-assisted thoracic surgery preoperative localization of small pulmonary nodules by using ZT medical glue (2-octyl cyanoacrylate)

Cited by 17 publications

References 13 publications

Comparison of hook-wire and medical glue for CT-guided preoperative localization of pulmonary nodules

Comparison of hook-wire and medical glue for CT-guided preoperative localization of pulmonary nodules

A novel technique for preoperative localization of pulmonary nodules using a mixture of tissue adhesive and iohexol under computed tomography guidance: A 140 patient single‐center study

CT Guided Placement of the End of the Microcoil in the Pleural Cavity: A More Helpful Method for Video-Assisted Thoracic Surgery (VATS) Resection of Ground Glass Opacity (GGO)

Contact Info

Product

Resources

About