A sacro‐caudal spinal cord choroid plexus papilloma in a shar‐pei dog

Abstract

A seven-year-old shar-pei dog was referred because of severe lumbosacral pain and faecal incontinence of 20 days' duration. Neurological examination was characterised by plegic tail, absence of perineal reflex, dilated anus, perineum and tail analgesia, and severe lumbosacral pain. The neurological clinical signs were suggestive of a selective lesion involving sacral and caudal spinal cord segments and/or related nerve roots. A magnetic resonance imaging of lumbosacral spine was performed and was suggestive of an intradural lesion. Primary or secondary neoplasia was considered as the most probable differential diagnosis. The dog was euthanased upon the owner's request. Histopathological examination confirmed the presence of an intradural-extramedullary neoplastic tissue enveloping intradural tract of spinal nerve roots. On the basis of histological and immunohistochemical findings, a diagnosis of well-differentiated choroid plexus papilloma was made. To the authors's knowledge, this is the first case of primary or metastatic spinal choroid plexus papilloma in dogs.

Clinical, magnetic resonance imaging, and histological description of a choroid plexus papilloma with disseminated intraventricular and spinal cerebrospinal fluid drop metastases in a young adult dog: a case report

“…According to the published literature in veterinary medicine, the median age of dogs diagnosed with CPP is 5 years (ranging from 3 to 14 years) (3,4,15,(17)(18)(19)(20)(21)(22)(23). Our patient is the youngest dog diagnosed with CPP.…”

“…Spinal CPPs have been rarely documented in dogs and cats (15)(16)(17). Their MRI features are, therefore, only rarely described.…”

“…Their MRI features are, therefore, only rarely described. Secondary spinal CPPs are reported as extramedullaryintradural space-occupying lesions (15)(16)(17). Compared to spinal cord parenchyma, spinal CPPs are hyperintense in T2w images and iso-to hypointense in T1w images (15)(16)(17).…”

“…Secondary spinal CPPs are reported as extramedullaryintradural space-occupying lesions (15)(16)(17). Compared to spinal cord parenchyma, spinal CPPs are hyperintense in T2w images and iso-to hypointense in T1w images (15)(16)(17). After contrast-medium administration, the lesions are markedly contrast-enhancing (15)(16)(17).…”

“…In human medicine, CSF drop metastases secondary to CPP have been reported, though rarely (13,14). In the veterinary literature, two case reports of spinal CPP without the identification of a primary CPP have been published (15,16). There are only two reports in the veterinary literature of a single small subarachnoid metastasis secondary to CPP only observed on post-mortem examination (4,7).…”