A role of cervical Pap smear as a screening tool in diagnosis of lesions of cervix&amp;#151;a one-year study

Patel, C. A.; Shah, Pinal; Bhagat, Vasudha

doi:10.5455/ijmsph.2016.30122015340

Cited by 8 publications

(17 citation statements)

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“…In this study, the mean age of patients with epithelial cell abnormality smears was in 42.8 years, which is similar to study done by Patel et al [8] -42.7%, Bamanikar et al [11] in which it was 38.5 years.…”

Section: Discussionsupporting

confidence: 88%

“…Out of these inflammatory lesions were 628 cases (65.01%), ASCUS were 228 cases (23.60%), LSIL were 62 cases (6.41%), HSIL were 28 cases (2.89%) and malignancy seen in 20 cases (2.07%). In the study done by Patel et al [8], epithelial cell abnormalities such as ASCUS, ASC-H, LSIL, HSIL, AGC, and carcinoma were noted to be 4.6%, which was comparable to the study done by Altaf et al, [13] Shekhar et al, [9] and Bamanikar et al [14] in which the percentage of epithelial cell abnormality noted was 3.1%, 6.7%, and 5.36%, respectively; however, Sarma et al [11] found higher rate of 11.95%. This may be because of widespread difference in the prevalence of risk factors and difference in availability of screening program.…”

Section: Discussionmentioning

confidence: 97%

“…[7] In our study, maximum number of patients (326) were in the age group of 31-40 years followed by 41-50 years. A study done by Patel et al [8] reported that maximum number of patients 653 (36.1%) were in the age group of 31-40 years followed by 477 cases (26.4%) in the age group of 15-30 years. Similar findings were also noted by Suryawanshi et al, [6] Shekhar et al, [9] and Rana et al [10] in which most common age group screened was 31-40 years and the percentage was 31.21%, 41.9%, and 43.7%, respectively…”

Section: Discussionmentioning

confidence: 97%

“…The common presenting complaint was white discharge per vaginum (leucorrhoea) in 760 cases followed by abdominal pain in 110 cases. A study done by Patel et al [8] reported that the common presenting complaint was white discharge per vaginum (leucorrhoea) in 376 (20.8%) followed by abdominal pain in 312 (17.3%) patients. Out of the 1808 cases, 1563 (86.45%) were reported as negative for any intraepithelial lesion or malignancy.…”

Section: Discussionmentioning

confidence: 99%

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Role of Pap Smear as a Screening Test in Precancerous and Cancerous Lesions of Cervix.

Raja

Bodhireddy

2019

IJMBS

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Introduction: A pap smear is a simple, co-effective, non invasive screening test in detecting precancerous and cancerous lesion of cervix and also useful for early detection and implementation of appropriative treatment in pre invasive cervical lesions. Early epithelial changes are recognised by pap smear test. Based on pap smear results to educate the women regarding symptoms of cervical cancer. Aim: Based on results of study, to differentiate between pre invasive and invasive carcinoma of cervix. Materials and Methods: The present study was done over a period of three years period (February 2016 - January 2019). The total number of 966 cases was studied in department of pathology, Government medical college, Kadapa. All the cases were categorised based on cyto-morphological features of pap smear. Requirement of materials: Cervical smears, coupling jars, suitable fixative is Isopropyl alcohol, Alcohol fixed slides were taken for Papanicolaou stain. Results: The present study done on total 966 cases, out of these inflammatory lesions were 628 cases (65.01%), ASCUS were 228 cases (23.60%), LSIL were 62 cases (6.41%), HSIL were 28 cases (2.89%) and malignancy seen in 20 cases (2.07%). Predominate age group in ASCUS and LSIL was fourth decade. HSIL was seen in Fifth decade. Depending on clinical data predominant cases 760cases (78.67%) were presented with leucorrhoea. Keywords: Cervical smears, Papanicolaou stain, Cervical lesions

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Role of Pap Smear as a Screening Test in Precancerous and Cancerous Lesions of Cervix.

Raja

Bodhireddy

2019

IJMBS

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“…[1] Majority (83%) of the cases occur in developing countries which possess only 5% of global resources. [2] India is a high-risk country for cervical cancer, accounting for more than quarter (26.1-43.8%) of the world's burden.…”

Section: Introductionmentioning

confidence: 99%

Potential of visual inspection with acetic acid as a screening test in comparison to conventional papanicolaou smear in detection of colposcopic biopsy proven cervical intraepithelial neoplasia: A tertiary centre experience

Bajaj¹,

Ahmad²,

Trivedi³

2017

Int J Med Sci Public Health

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INTRODUCTIONAs per population-based cancer registries in India, cervical carcinoma is the second most common cancer among women after breast cancer.[1] Majority (83%) of the cases occur in developing countries which possess only 5% of global resources.[2] India is a high-risk country for cervical cancer, Background:Although it is well established that organized cytological screening programs are the mainstay for cancer cervix control but the financial and logistic burden of operating such a program is considerable. This has prompted the evaluation of alternative feasible techniques. Early and ongoing comparative studies worldwide showed visual inspection with acetic acid (VIA) as potential alternatives to cervical cytology because of their low cost, the ease of use, high sensitivity and immediate result allowing "see and treat" at first visit. Objectives: To evaluate the performance of VIA and its comparison with cytology in cervical cancer screening. Materials and Methods: A total of 400 non-pregnant reproductive age women were subjected to papanicolaou Pap smear) and VIA in this prospective study done in a tertiary-care centre in Delhi. Reference standard used for all was colposcopy and colposcopic-directed biopsy (when required). Results: Of 400 Pap smears done 11.75% were normal, 77.5% inflammatory, 5.5% had atypical squamous cells (ASC) atypical glandular cells of undetermined significance (AGUS), 0.25% ASC-H, 0.5% AGUS, 2% low-grade squamous intraepithelial lesions (LSIL), 1.5% high-grade squamous intraepithelial lesion (HSIL), and invasive cancer in 0.5%. With LSIL and above smears as significant, the sensitivity and specificity of Pap were 50% and 97.66%, respectively. VIA was positive according to two thresholds. When high-threshold was used then only well demarcated, opaque white areas near the squamocolumnar junction were taken as positive whereas in low-threshold criterion faint or ill-defined ace to white anywhere and well-defined areas away from squamocolumnar junction was also taken as positive. 29.3% were positive with low-threshold criterion for VIA and 9.3% with high-threshold criterion. The sensitivity with low-threshold criteria was 100% and specificity 72.7%. Conclusion: The sensitivity with low-threshold criteria was 100% and specificity 72.7%. With high-threshold sensitivity and specificity were 85.7% and 95%, respectively. Conclusion: VIA with low-threshold criteria had high sensitivity (100%), but specificity (72.7%) was low, but with high-threshold criteria for positivity, the specificity increases up to 95% which is comparable to cytology. The gynecologists in tertiary-care centers can use the high-threshold criterion effectively, and patient with significant lesions can be directly subjected to further treatment at the earliest thus reducing loss to follow-up.

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Cervical Pap Smear Pattern- Comparison of Hospital and Screening Camp Population

B¹,

Balakrishnan²,

Sankar³

2019

jemds

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BACKGROUND Cervical cancer is one of the leading causes of mortality and morbidity among women worldwide. In India it accounts for 25% of cancer deaths. Only limited number of studies are available on prevalence of cervical epithelial abnormalities, especially in Kerala. The objective of the study was to estimate the prevalence of cervical cytological pattern in central Kerala, so that appropriate screening strategies can be planned. MATERIALS AND METHODS A one-year descriptive study was conducted on cervical pap smears in study population groups: 1) camp population from various camps conducted in and around Kottayam and 2) hospital population and specimens received in the department of Pathology, Government Medical College, Kottayam during the study period of 12 months. Smears were assessed according to the revised Bethesda System 2014. A total of 240 cases of Pap smears were analysed in each group of population (hospital and screening camp). RESULTS The mean age of population in the present study was 48.20 ± 10.224 SD in camp and 48.23 ± 11.339 SD in hospital population. Majority belongs to the age group 41-50 years. In both, majority of the smears were negative for intraepithelial lesion or malignancy (NIL/M). Epithelial abnormality was seen in 1.25% cases (LSIL) of camp population & 2.5% cases (ASC-US, LSIL and HSIL 0.80% each) of hospital population. CONCLUSION Our study shows a relatively low prevalence of cervical epithelial abnormality similar to developed countries. Pap smear is an effective screening procedure to detect cervical cytological abnormalities. Routine screening should be offered to all women above 21 years. It is recommended to improve awareness about disease among females.

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A role of cervical Pap smear as a screening tool in diagnosis of lesions of cervixa one-year study

Cited by 8 publications

References 0 publications

Role of Pap Smear as a Screening Test in Precancerous and Cancerous Lesions of Cervix.

Role of Pap Smear as a Screening Test in Precancerous and Cancerous Lesions of Cervix.

Potential of visual inspection with acetic acid as a screening test in comparison to conventional papanicolaou smear in detection of colposcopic biopsy proven cervical intraepithelial neoplasia: A tertiary centre experience

Cervical Pap Smear Pattern- Comparison of Hospital and Screening Camp Population

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