2022
DOI: 10.3390/cancers14215327
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A Robust Personalized Classification Method for Breast Cancer Metastasis Prediction

Abstract: Accurate prediction of breast cancer metastasis in the early stages of cancer diagnosis is crucial to reduce cancer-related deaths. With the availability of gene expression datasets, many machine-learning models have been proposed to predict breast cancer metastasis using thousands of genes simultaneously. However, the prediction accuracy of the models using gene expression often suffers from the diverse molecular characteristics across different datasets. Additionally, breast cancer is known to have many subt… Show more

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Cited by 4 publications
(2 citation statements)
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“…Second, setting the number of species of a classifier too large greatly reduces the accuracy of the predictions obtained from the model in the presence of noise and insufficiently distinctive fault characteristics [7].…”
Section: Data Design and Generation For Convolutional Neural Network ...mentioning
confidence: 99%
“…Second, setting the number of species of a classifier too large greatly reduces the accuracy of the predictions obtained from the model in the presence of noise and insufficiently distinctive fault characteristics [7].…”
Section: Data Design and Generation For Convolutional Neural Network ...mentioning
confidence: 99%
“…Synthetic dataset 1 represents the most ideal scenario, characterized by two additional features exhibiting predictive power over different regions of the initial features value space, as shown in Figure 3. Conversely, synthetic dataset 2 illuminates the necessity for sample-weighted inference (as indicated by LW) when confronted with non-linear predictive regions highlighted in Figure 4 24,25 . Furthermore, synthetic dataset 3 serves as a testament to the robustness of our framework, particularly in scenarios involving overlapping regions on the initial features value space that can be seen in Figure 5.…”
Section: Reasoning Process Of the Frameworkmentioning
confidence: 99%