“…Ynamides, displaying an optimal balance of stability and reactivity, have become a privileged building blocks for the synthesis of highly versatile nitrogen‐containing molecules including bioactive agents and natural products, Accordingly, many synthetic strategies for ynamides have been developed since the first synthesis by Viehe in 1972 . Among all of these known methods, arguably one of the best routes to ynamides was the copper‐catalyzed amidation of alkynyl bromides by Hsung . However, this strategy, as well as others, tends to require dry organic solvents (e.g., toluene, DMF, DMSO, DCM) and relatively high temperatures.…”