A robust method for simultaneous determination of eight B vitamins in human serum by liquid chromatography tandem mass spectrometry
Yu‐Mei Huo,
Shang‐Qing Zhang,
Gao‐Ping Wu
et al.
Abstract:The level of vitamin B group in human serum is an important index of human health. Among B vitamins, cyanocobalamin in serum is unstable and its content is extremely low. Rapid and simultaneous detection of multiple B vitamins including cyanocobalamin is a challenge. Herein, we have developed a rapid and stable method that can realize the determination of thiamine, riboflavin, nicotinamide, pantothenic acid, pyridoxic acid, biotin, 5‐methyltetrahydrofolate, and cyanocobalamin simultaneously in 6 min. The metho… Show more
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