A robotic object hitting task to quantify sensorimotor impairments in participants with stroke

Tyryshkin, Kathrin; Coderre, Angela M; Glasgow, Janice I.; Herter, Troy M.; Bagg, Stephen; Dukelow, Sean P.; Scott, Stephen H.

doi:10.1186/1743-0003-11-47

Cited by 84 publications

(124 citation statements)

References 48 publications

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“…Position matching (PM) is a test of proprioception (position sense), in which the robot moves the stroke‐affected arm to 1 of 9 locations, and the subject is instructed to move their other arm to the mirror‐image location with vision occluded 29, 30. Object hit (OH) is a test of bimanual sensorimotor control in which participants use virtual paddles at their fingertips to hit away balls that move toward them at increasing speed and frequency 31. Object hit and avoid (OHA) is similar to OH, except that subjects are instructed to only hit 2 specific shapes while 6 other shapes serve as distractors, thus requiring higher cognitive skills 32.…”

Section: Methodsmentioning

confidence: 99%

Differential Impact of Acute Lesions Versus White Matter Hyperintensities on Stroke Recovery

Hawe

Findlater

Kenzie

et al. 2018

JAHA

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BackgroundUnderstanding how the size of acute lesions and white matter hyperintensities (WMH) impact stroke recovery can improve our ability to predict outcomes and tailor treatments. The aim of this exploratory study was to investigate the role of acute lesion volume and WMH volume on longitudinal recovery of specific sensory, motor, and cognitive impairments after stroke using robotic and clinical measures.Methods and ResultsEighty‐two individuals were assessed at 1, 6, 12, and 26 weeks poststroke with robotic tasks and commonly used clinical measures. The volumes of acute lesions and WMH were measured on fluid‐attenuated inversion recovery images. Linear mixed models were used to investigate the role of acute lesions and WMH on parameters derived from the robotic tasks and clinical measures. Regression analysis determined the added value of acute lesion and WMH volumes along with measures of initial performance to predict outcomes at 6 months. Acute lesion volume has widespread effects on sensory, motor, and overall functional recovery poststroke. The impact of WMH was specific to cognitive impairments. Apart from the robotic position sense task, neither lesion volume nor WMH measure had significant ability to predict outcomes at 6 months over using initial impairment as measured by robotic assessments alone.ConclusionsWhile acute lesion volume and WMH may impact different impairments poststroke, their clinical utility in predicting outcomes at 6 months poststroke is limited.

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Section: Methodsmentioning

confidence: 99%

Differential Impact of Acute Lesions Versus White Matter Hyperintensities on Stroke Recovery

Hawe

Findlater

Kenzie

et al. 2018

JAHA

View full text Add to dashboard Cite

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“…Subjects performed 4 individual robotic tasks assessing position sense 14 ( Figure 1A), kinesthesia 15 ( Figure 1B), motor function of the affected arm 21 ( Figure 1C), and simultaneous motor function of both arms 25 ( Figure 1D). For all tasks, subjects sat in the wheelchair base of the robotic exoskeleton (KINARM; BKIN Technologies Ltd, Kingston, Ontario, Canada) with their arms supported against gravity.…”

Section: Robotic Assessmentsmentioning

confidence: 99%

“…In the object hit task (OH) 25 ( Figure 1D), subjects viewed virtual paddles at the position of each index finger and were instructed to hit balls moving toward them away from the body. We measured 12 parameters known to quantify unimanual and bimanual motor behavior with OH 25 : (1) total hits, (2) hand bias hits, (3) miss bias, (4) hand transition, (5) hand selection overlap, (6) median error, (7) and (8) speed of the affected or unaffected hand, (9) hand speed bias, (10) and (11) movement area of the affected or unaffected hand, and (12) movement area bias.…”

Section: Robotic Measures Of Motor Controlmentioning

confidence: 99%

Examining Differences in Patterns of Sensory and Motor Recovery After Stroke With Robotics

Semrau

Herter

Scott

et al. 2015

Stroke

109

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Background and Purpose-Developing a better understanding of the trajectory and timing of stroke recovery is critical for developing patient-centered rehabilitation approaches. Here, we quantified proprioceptive and motor deficits using robotic technology during the first 6 months post stroke to characterize timing and patterns in recovery. We also make comparisons of robotic assessments to traditional clinical measures. Methods-One hundred sixteen subjects with unilateral stroke were studied at 4 time points: 1, 6, 12, and 26 weeks post stroke. Subjects performed robotic assessments of proprioceptive (position sense and kinesthesia) and motor function (unilateral reaching task and bimanual object hit task), as well as several clinical measures (Functional Independence Measure, Purdue Pegboard, and Chedoke-McMaster Stroke Assessment). Results-One week post stroke, many subjects displayed proprioceptive (48% position sense and 68% kinesthesia) and motor impairments (80% unilateral reaching and 85% bilateral movement). Interindividual recovery on robotic measures was highly variable. However, we characterized recovery as early (normal by 6 weeks post stroke), late (normal by 26 weeks post stroke), or incomplete (impaired at 26 weeks post stroke). Proprioceptive and motor recovery often followed different timelines. Across all time points, robotic measures were correlated with clinical measures. Conclusions-These results highlight the need for more sensitive, targeted identification of sensory and motor deficits to optimize rehabilitation after stroke. Furthermore, the trajectory of recovery for some individuals with mild to moderate stroke may be much longer than previously considered.

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“…This task assesses spatial attention, sensorimotor control and planning of the upper limbs. 23 Object hit and avoid: This task is similar to the Object Hit task, however at the beginning of the task the participant observes two shapes (e.g. triangle and horizontal rectangle).…”

Section: Reverse Visually Guided Reaching (Inverted)mentioning

confidence: 99%

Assessing the relationship between brain tissue oxygenation and neurological dysfunction in critically ill patients: study protocol

et al. 2016

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Background: Acute and chronic neurological complications amongst survivors of critical illness is common, however, the underlying etiology of this neurological dysfunction is unknown. This is the first study to use near-infrared spectroscopy to non-invasively measure brain tissue oxygenation, as a surrogate marker of cerebral perfusion, and correlate these values with subsequent neurological dysfunction. We will test the hypothesis that poor cerebral oxygenation during the first 24 hours of critical illness is correlated with acute and chronic neurological complications.Methods: This single-centre prospective observational study will be performed in a 33-bed medical/surgical intensive care unit (ICU). Adult patients are eligible for enrolment if they are admitted to the ICU within 24 hours, require mechanical ventilation, and/or vasopressor support. For 24 hours, cerebral oxygenation levels will be measured with the FORESIGHT oximeter; vital signs and tissue oxygenation will be captured with data monitoring software. Participants will be screened daily for delirium with the confusion assessment method-ICU. Long-term neurological function will be assessed with the Repeatable Battery for the Assessment of Neuropsychological Status and the kinesiological instrument for normal and altered reaching movements (KINARM) robot.Conclusions: This study will provide novel information regarding the determinants of cerebral oxygenation during the acute phase (i.e. 24 hours) of critical illness, and its potential relationship with subsequent neurological complications. Should a relationship exist between cerebral oxygenation and neurological complications, future studies will be aimed at using brain tissue oxygenation as a therapeutic target to prevent acute and chronic neurological dysfunction. Clinical Trial Registration: This trial is registered on clinicaltrials.gov (Identifier: NCT02344043), retrospectively registered January 8, 2015.

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A robotic object hitting task to quantify sensorimotor impairments in participants with stroke

Cited by 84 publications

References 48 publications

Differential Impact of Acute Lesions Versus White Matter Hyperintensities on Stroke Recovery

Differential Impact of Acute Lesions Versus White Matter Hyperintensities on Stroke Recovery

Examining Differences in Patterns of Sensory and Motor Recovery After Stroke With Robotics

Assessing the relationship between brain tissue oxygenation and neurological dysfunction in critically ill patients: study protocol

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