A Review on the use of Synthetic and Recombinant Antigens for the
Immunodiagnosis of Tegumentary Leishmaniasis
Kamila Alves Silva,
Anna Júlia Ribeiro,
Isadora Braga Gandra
et al.
Abstract:Improving the diagnostic technology used to detect tegumentary leishmaniasis
(TL) is essential in view of it being a widespread, often neglected tropical disease
with cases reported from the southern United States to northern Argentina. Recombinant
proteins, recombinant multiepitope proteins, and synthetic peptides have been extensively
researched and used in disease diagnosis. One of the benefits of applying these antigens
is a measurable increase in sensitivity and specificity, which improves test accuracy.
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