2021
DOI: 10.3390/ijms222111787
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A Review on the Role of Stem Cells against SARS-CoV-2 in Children and Pregnant Women

Abstract: Since the COVID-19 outbreak was acknowledged by the WHO on 30 January 2020, much research has been conducted to unveil various features of the responsible SARS-CoV-2 virus. Different rates of contagion in adults, children, and pregnant women may guide us to understand the underlying infection conditions of COVID-19. In this study, we first provide a review of recent reports of COVID-19 clinical outcomes in children and pregnant women. We then suggest a mechanism that explains the curious case of COVID-19 in ch… Show more

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“…To address this problem, effective tests must be put in place for the rapid recognition of bacterial or viral diseases [ 13 ]. In this field, microbiological research needs to be expanded for adjuvant therapy with bacterial strains that are beneficial to the human microbiota, and which use probiotics and stem cells during viral infection [ 32 , 33 , 34 , 35 , 36 ]. Moreover, because the aspiration of oral bacteria induces the expression of angiotensin-converting enzyme 2, a receptor for SARS-CoV-2, and production of inflammatory cytokines in the lower respiratory tract, poor oral hygiene can lead to COVID-19 aggravation [ 37 , 38 , 39 , 40 , 41 ].…”
Section: Microbiological Perspectives In Pandemicsmentioning
confidence: 99%
“…To address this problem, effective tests must be put in place for the rapid recognition of bacterial or viral diseases [ 13 ]. In this field, microbiological research needs to be expanded for adjuvant therapy with bacterial strains that are beneficial to the human microbiota, and which use probiotics and stem cells during viral infection [ 32 , 33 , 34 , 35 , 36 ]. Moreover, because the aspiration of oral bacteria induces the expression of angiotensin-converting enzyme 2, a receptor for SARS-CoV-2, and production of inflammatory cytokines in the lower respiratory tract, poor oral hygiene can lead to COVID-19 aggravation [ 37 , 38 , 39 , 40 , 41 ].…”
Section: Microbiological Perspectives In Pandemicsmentioning
confidence: 99%