A review on the physicochemical and biological applications of biosurfactants in biotechnology and pharmaceuticals

Abbot, Vikrant; Paliwal, Diwakar; Sharma, Anuradha; Sharma, Poonam

doi:10.1016/j.heliyon.2022.e10149

Cited by 36 publications

(12 citation statements)

References 149 publications

(135 reference statements)

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“…To this, glycolipid-based surfactants such as rhamnolipids, sophorolipids, mannosyl-erythritol lipids and trehalolipids offer structural diversity and multifunctionality presenting them as great application within cosmetics industry. Because of their low molecular weight, they reduce surface tension and interfacial tension across solids, liquids and gases, as well as enhance the solubility of hydrophobic substances in water ( Abbot et al, 2022 ). This unique functionality of the above mentioned different classes of biosurfactants and their specific applications in home and personal care industry is discussed below.…”

Section: Biosurfactants In the Home And Personal Care Industrymentioning

confidence: 99%

Advances in the production of biosurfactants as green ingredients in home and personal care products

Nasser,

Sharma,

Kaur

2024

Front. Chem.

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Home and personal care industry is currently witnessing a growing demand for sustainable and eco-friendly alternatives to synthetic surfactants. This increase is fueled by concerns over the delayed degradation and environmental impact of the latter. To this, biosurfactants possess important properties such as biodegradability, low toxicity, and renewable sourcing. These qualities position them as compelling replacements of traditional synthetic surfactants. Their diverse attributes including emulsification, antimicrobial efficacy, surface tension reduction, and foaming capability, make them well-suited choices for home and personal care products. Biosurfactants can be produced through several inexpensive and renewable sources which contributes to their commercialization potential. This article discusses various microbial derived biosurfactants including rhamnolipids, sophorolipids, mannosyl-erythritol lipids, trehalolipids and lipopeptides, unraveling and comparing their distinctive roles and advantages in the home and personal care industry. It also focuses on the recent patent innovations in the production of biosurfactants which have aimed at improving their economic viability and performance attributes. Finally, the article sheds light on the challenges and future trajectories for better integration of these sustainable biosurfactants into mainstream consumer products.

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Section: Biosurfactants In the Home And Personal Care Industrymentioning

confidence: 99%

Advances in the production of biosurfactants as green ingredients in home and personal care products

Nasser,

Sharma,

Kaur

2024

Front. Chem.

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“…Biosurfactants are surface‐active chemicals derived from microorganisms and have various applications in different industries [156] . However, it is crucial to ensure their stability and proper storage conditions to utilize biosurfactants effectively.…”

Section: Application Of Biosurfactantmentioning

confidence: 99%

“…Biosurfactants are surface-active chemicals derived from microorganisms and have various applications in different industries. [156] However, it is crucial to ensure their stability and proper storage conditions to utilize biosurfactants effectively. The stability of biosurfactants is influenced by factors such as pH, temperature, salinity, enzymes, and organic solvents.…”

Section: Stability and Storage Of Biosurfactantmentioning

confidence: 99%

Prospects of Microbial Bio‐surfactants To Endorse Prolonged Conservation in the Pharmaceutical and Agriculture Industries

Karnwal

2023

ChemistrySelect

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Chemical surfactants have raised concerns due to their negative impact on ecosystems, prompting the search for ecofriendly alternatives. Biosurfactants derived from microorganisms offer a promising solution. These biomolecules are less harmful and can replace toxic pesticide surfactants. Biosurfactants have shown potential in agriculture for food digestion, crop protection, soil fertility, disease management, antibacterial properties, and biofilm prevention. They eliminate plantpathogens and improve nutrient availability, supporting plantgrowth. Rhamnolipids, produced by Pseudomonas, reduce surface tension, are used as wetting agents and emulsifiers in agriculture, and antimicrobial and anti-inflammatory medications. Surfactin, a biosurfactant from Bacillus subtilis, improves plant development, controls plant diseases, and fights pathogens and diseases. Candida bombicola yeast produces sopho-rolipids, biodegradable surfactants with antibacterial, anticancer, and anti-inflammatory properties. Pseudozyma yeast produces mannosylerythritol lipids (MELs), which biocontrol fungus and have antibacterial, anticancer, and immunomodulatory activities. Biosurfactants also hold potential in pharmaceuticals, functioning as antioxidants, exhibiting antibacterial and anticancer activities, and acting as drug-delivery systems. However, challenges in biosurfactant production include varying research methods, limited production organism sources, and cost implications for large-scale manufacturing. This minireview explores microbiologically produced biosurfactants, their regulatory parameters, their applications in optimizing soil health and controlling plant infections, and their potential roles in the pharmaceutical sector.* Ability to tolerate high temperatures, * Ability to tolerate variation in pH, * Ability to tolerate saline environment, * Biodegradable character, * Low or non-toxic nature, and * Effective selectivity.Generally, biosurfactants are amphipathic molecules characterized by hydrophobic and hydrophilic components. Generally, the hydrophobic component consists of a very long chain of fatty acids connected. The hydrophilic component comprises positively, negatively, or amphoterically charged ions. In contrast to their chemical analogs, biosurfactants are often categorized by their CMC concentration, low or high molecular weight, the microorganism type that produce biosurfactant, and their mode of action. Low molecular weight biosurfactants are most frequently reported as glycolipids, phospholipids, and [a]

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“…With a multitude of discoveries executed for the utilization of various secondary metabolites produced by actinomycetes due to their eco-friendly and economical facet, only a handful of research has been invested in the search for another type of secondary metabolite from actinomycetes, which is the production of biosurfactants. Biosurfactants are amphiphilic surface-active compounds synthesized by living organisms such as bacteria, yeasts, and fungi, and serve as key ingredients in various industrial sectors such as petroleum and organic chemicals, foods and pharmaceuticals, metallurgy and fertilizers, and environmental control [3]. Compared with the common petroleum-based synthetic surfactants, biosurfactants produced by bacteria, also known as microbial surfactants, are biodegradable, less toxic, effective at low concentrations, and show potency in bioremediation [4].…”

Section: Introductionmentioning

confidence: 99%

Screening biosurfactant‐producing actinomycetes: Identification of Streptomyces sp. RP1 as a potent species for bioremediation

Ayoib,

Gopinath,

Zambry

et al. 2024

J Basic Microbiol

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This study aimed to isolate biosurfactant‐producing and hydrocarbon‐degrading actinomycetes from different soils using glycerol–asparagine and starch–casein media with an antifungal agent. The glycerol–asparagine agar exhibited the highest number of actinomycetes, with a white, low‐opacity medium supporting pigment production and high growth. Biosurfactant analyses, such as drop collapse, oil displacement, emulsification, tributyrin agar test, and surface tension measurement, were conducted. Out of 25 positive isolates, seven could utilize both olive oil and black oil for biosurfactant production, and only isolate RP1 could produce biosurfactant when grown in constrained conditions with black oil as the sole carbon source and inducer, demonstrating in situ bioremediation potential. Isolate RP1 from oil‐spilled garden soil is Gram‐staining‐positive with a distinct earthy odor, melanin formation, and white filamentous colonies. It has a molecular size of ~621 bp and 100% sequence similarity to many Streptomyces spp. Morphological, biochemical, and 16 S rRNA analysis confirmed it as Streptomyces sp. RP1, showing positive results in all screenings, including high emulsification activity against kerosene (27.2%) and engine oil (95.8%), oil displacement efficiency against crude oil (7.45 cm), and a significant reduction in surface tension (56.7 dynes/cm). Streptomyces sp. RP1 can utilize citrate as a carbon source, tolerate sodium chloride, resist lysozyme, degrade petroleum hydrocarbons, and produce biosurfactant at 37°C in a 15 mL medium culture, indicating great potential for bioremediation and various downstream industrial applications with optimization.

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A review on the physicochemical and biological applications of biosurfactants in biotechnology and pharmaceuticals

Cited by 36 publications

References 149 publications

Advances in the production of biosurfactants as green ingredients in home and personal care products

Advances in the production of biosurfactants as green ingredients in home and personal care products

Prospects of Microbial Bio‐surfactants To Endorse Prolonged Conservation in the Pharmaceutical and Agriculture Industries

Screening biosurfactant‐producing actinomycetes: Identification of Streptomyces sp. RP1 as a potent species for bioremediation

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