A Review on the Biomedical Applications of Alumina

Al-Moameri, Harith; Nahi, Zainab Majid; Rzaij, Dina Raheem; Al-Sharify, Noor T.

doi:10.31272/jeasd.24.5.5

Cited by 8 publications

(6 citation statements)

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“…As a result, α-alumina implants can undergo loosening and develop fibrosis, also known as fibrous encapsulation. This is a protective mechanism, where fibrous tissue forms to isolate the implant from the biological system, which may lead to complete encapsulation of the implant over time [45]. Therefore, it is reason that the use of pure α-alumina is a big challenge, and the great interest to use alumina is as a base for bioactive composites or as a support for the deposition of bioactive materials [21].…”

Section: Composite With Hydroxyapatitementioning

confidence: 99%

Alumina applied in bone regeneration: Porous α-alumina and transition alumina

et al. 2022

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Alumina is a polymorphic bioceramic that has been extensively investigated for application in bone regeneration. Dense α-alumina has been considered a suitable biomaterial for dental and orthopedic implants due to its superior mechanical properties. However, its use is limited due to its high inertia in a biological environment. Recent investigations have focused on its distinct phases and surface characteristics through the control of morphology, physical properties, and chemical composition to enhance bioactivity. This article presents a brief review of the developments in porous α-alumina and amorphous-γ-alumina transition. Most studies have shown that composites and alumina coated with bioactive materials, high surface area, and hydroxylated surface can significantly improve biological properties. Cellular responses such as fixation, growth, and proliferation, as well as biomineralization, are the main studies to validate improvements in bioactive properties.

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Section: Composite With Hydroxyapatitementioning

confidence: 99%

Alumina applied in bone regeneration: Porous α-alumina and transition alumina

et al. 2022

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“…Furthermore, alumina is used in construction, fuel cells, abrasive or chemical waste cleaners, microelectronics, etc. In addition to its excessive hardness, electrical resistance, corrosion resistance, and refractoriness, alumina is an inert material with the highest biocompatibility currently used in the clinical field [13,14].…”

Section: Introductionmentioning

confidence: 99%

“…Al-Moameri et al [13] investigated the biological uses of alumina and found that it is quite inactive and corrosion-resistant. Alumina applies smoothly for several years and causes little tissue reaction.…”

Section: Introductionmentioning

confidence: 99%

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Investigation of Microstructure and Mechanical Properties of Layered Material Produced by Adding Al2O3 to 316L Stainless Steel

Albahlol,

Elkilani,

Çuğ

et al. 2023

Metals

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This study developed new advanced composite materials consisting of functional grading of 316L and Al2O3 specially designed for potential biomedical applications. Mechanical properties were characterized by tensile testing, and microstructural properties by optical microscope, scanning electron microscope (SEM), and Energy Dispersive X-Ray (EDX) analyses. The uniform mixture in the material, up to 40% by weight of Al2O3, is uniformly distributed in the 316L matrix that shows disintegration. Then, samples with 2, 3, 4, and 5 layers were produced in functionally graded 6, 7, 8, and 9 material types, respectively. The layer thicknesses were formed with an average of 900 µm. The results show that new composite materials can be produced functionally using 316L and Al2O3 in a layered manner. As a result of the mechanical experiments, it has been observed that the tensile strength of the layered composite structures remains within the range of 91–191 MPa, depending on the layer type. It has been observed that the elongation varies between 3.16 and 12.46%. According to these results, the materials obtained are considered suitable for use as an alternative prosthetic material in biomedical applications. The tensile strength, % elongation of the Composition 7, and yield strength of functionally graded (316 + (316L-10 Al2O3) + (316L-20 Al2O3) + (316L-30 Al2O3)) material are 123 megapascals (MPa), 7.3%, and 111MPa, respectively, and according to the literature, the mechanical strength of human bone is very close to this composition properties.

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“…Em aplicações biomédicas a AAN pode ser usada para o revestimento de metais como os utilizados em próteses para que se obtenha maior resistência à corrosão, baixo coeficiente de atrito e bioatividade (27,28). O coeficiente de atrito pode ser alterado por injeção de nanopartículas de ativos com o objetivo de aumentar a abrasividade do material.…”

Section: Aplicações Da Alumina Anódica Nanoporosaunclassified

Obtenção de alumina anódica nanoporosa em liga AA 1050

Oliveira¹

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Agradeço primeiramente a Deus, pela força a mim dada nesta jornada árdua.Dedico este trabalho à minha mãe e aos meus filhos, que me apoiaram incondicionalmente, pelo carinho, esforço, dedicação e compreensão ao longo desta caminhada.Agradeço à minha orientadora, Prof.ª Dr.ª Marina Fuser Pillis, pela contribuição cientifica, amizade, oportunidade e, principalmente, pela confiança, paciência e incentivo a pesquisa, ajudando-me a organizar as ideias com coerência. Agradeço aos meus colegas de laboratório quanto as palavras de incentivo que não foram poucas, a equipe proporcionou discussões relevantes para a conclusão deste trabalho, especialmente à duas pessoas ao Olandir Vercino Correa, pelo apoio, companhia e pelo conhecimento compartilhado durante todo o projeto e ao Rodrigo Teixeira Bento pelas experiências compartilhadas no caminho desta jornada e pela realização das análises de AFM. Agradeço aos colaboradores do CCTM-IPEN Rene Ramos de Oliveira e Marcos Yovanovich, pela realização das análises de DRX; a Glauson Aparecido Ferreira Machado pela realização das análises de MEV-FEG. Agradeço a Prof.ª Dr.ª Denise Freitas Siqueira Petri do Instituto de Química da USP, pelo auxílio na realização das medidas de ângulo de contato em conjunto Victor Basile Astuto e Alfredo Duarte pela realização das análises de MEV-FEG. Agradeço, por fim, aos professores, funcionários e ao Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN/SP) da USP como um todo pela oportunidade proporcionada, estimulando o meu desenvolvimento intelectual, profissional e humano. 6 e 8 h em eletrólitos de 0,35 M H2SO4, 0,40 M H2SO4 e 0,45 M H2SO4. Observouse que a camada de AAN é amorfa e cresce perpendicularmente à superfície da amostra e que o aumento do tempo de anodização resultou em superfícies de maior molhabilidade, independente da concentração do eletrólito. Para uma dada concentração, a espessura da camada de alumina anódica aumenta com o aumento do tempo de anodização até 5 h de processo. O diâmetro médio de nanoporos variou entre 38 e 54 nm e a espessura da camada oxidada variou entre 42 e 200 m.

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A Review on the Biomedical Applications of Alumina

Cited by 8 publications

References 0 publications

Alumina applied in bone regeneration: Porous α-alumina and transition alumina

Alumina applied in bone regeneration: Porous α-alumina and transition alumina

Investigation of Microstructure and Mechanical Properties of Layered Material Produced by Adding Al2O3 to 316L Stainless Steel

Obtenção de alumina anódica nanoporosa em liga AA 1050

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