A Review on Polymeric Wound Dress for the Treatment of Burns and Diabetic Wounds

Abstract

Today, various commercial dressings have been developed and introduced to the market. The diversity makes it difficult for the nurse to choose the right type. Although the most important reason to use a wound dress is to protect the wound from infection and prevent infection, but in fact, the main purpose of using these materials is to speed up the wound healing process. Traumatic injuries result in an epithelial wound that disrupts the continuity of the skin surface. These differences reveal as abrasions, punctures, and injuries. Wounds are divided into two types; the skin is either cut or ruptured, including deep wounds and bruises, or surface wounds. Expedited wound healing has been considered since the archaic era of human civilization, with the earliest reported case from the Ancient Egyptians. Wound lesions in mummified humans were observed to be cover with animal skin, with signs of (primary/secondary) wound healing present. A "new wound dressing" is an advanced wound dress used in wound management as biocompatible and biodegradable biomaterials that heal wounds and burns. In the past, it was believed that dry wounds had expedited healing and wet wounds have been found to promote using re-epithelization and result in reduced scar formation. Wounds can be treated using various types of natural polymers and materials. Also, techniques like electrospinning and freeze-drying techniques can be used for the fabrication of standard wound dress. These wounds are associated with bandages, inflammation, bleeding, pain, and pus. In this work, we consider various types of wounds and techniques to treat the wound. Susceptibility to these areas, due to special symptoms for each of them. Products like hydrogels, hydrocolloids, films, sponges, and nano-fiber polymeric materials are used to promote healing. In this review, we examine the ideal products for the treatment of wounds in diabetic patients.

Antimicrobial Activity of Blow Spun PLA/Gelatin Nanofibers Containing Green Synthesized Silver Nanoparticles against Wound Infection-Causing Bacteria

“…Advanced wound dressing plays an important role in surface protection, control of bacteriostatic activity, moisture retention, and shortening of tissue recovery period due to its excellent wound dressing properties [ 15 , 16 ]. The main role of wound dressing includes maintaining wound hydration, absorbing excess wound secretions, minimizing the impact on the wound site, and as a barrier to the entry of foreign microorganisms into the wound site [ 17 , 18 , 19 ]. The nanofiber dressings as a product of nanotechnology were designed to decrease infection, irritation and improve wound healing by providing a positive environment in addition to their usual duties [ 20 , 21 ].…”

Highly active probiotic hydrogels matrixed on bacterial EPS accelerate wound healing via maintaining stable skin microbiota and reducing inflammation

“…Some microorganisms colonized in the skin can act as a physical barrier against pathogen invasion [ 3 , 4 ]. Once the skin is damaged, harmful bacteria take the opportunity to invade the tissue and disrupt the balance of the skin's microbial system, resulting in tissue damage and wound infection [ 5 ]. This inevitably disrupts the wound-healing process, imposing significant challenges on patients and healthcare providers.…”

Synthesis and characterization of a novel hydrogel based on carboxymethyl chitosan/sodium alginate with the ability to release simvastatin for chronic wound healing

“…They also leave particles and fiber residues in the wound. Therefore, concerns related to traditional dressings and their low performance in treating chronic wounds have led to studies on new types of wound dressings [7].…”