A Review on Polymer and Lipid-Based Nanocarriers and Its Application to Nano-Pharmaceutical and Food-Based Systems

Abstract

Recently, owing to well-controlled release, enhanced distribution and increased permeability, nanocarriers used for alternative drug and food-delivery strategies have received increasingly attentions. Nanocarriers have attracted a large amount of interest as potential carriers of various bioactive molecules for multiple applications. Drug and food-based delivery via polymeric-based nanocarriers and lipid-based nanocarriers has been widely investigated. Nanocarriers, especially liposomes, are more and more widely used in the area of novel nano-pharmaceutical or food-based design. Herein, we aimed to discuss the recent advancement of different surface-engineered nanocarriers type, along with cutting-edge applications for food and nanomedicine and highlight the alternative of phytochemical as nanocarrier. Additionally, safety concern of nanocarriers was also highlighted.

Ameliorative effect of gel combination of Centella asiatica extract transfersomes and rosemary essential oil nanoemulsion against UVB-induced skin aging in Balb/c mice

“…Osmotic force theory is the main mechanism associated with skin penetration of transfersomes 43 . Lipid-based nanocarriers systems are encapsulated into transfersomes and nanoemulsions for topical and transdermal drug delivery based on skin penetration, generally having a average particle size distribution between 1-100 nm 44 . In the present study, the particle size distributions of CA transfersomes and REO nanoemulsion were less than 70 nm.…”

Thermo-Sensitive Poly (N-isopropylacrylamide-co-polyacrylamide) Hydrogel for pH-Responsive Therapeutic Delivery

“…Cur can be made more stable, absorbed, and delivered to target sites by being encapsulated into bio-polymeric particles or conjugated with nanoparticles, for instance [ 4 , 5 , 6 ]. Due to their outstanding benefits in terms of biocompatibility, simplicity in design and preparation, their variety of structures, and intriguing bio-mimetic properties, polymers have been extensively used as nanocarriers in recent decades [ 7 , 8 , 9 , 10 ].…”

Carnosic Acid Encapsulated in Albumin Nanoparticles Induces Apoptosis in Breast and Colorectal Cancer Cells

“…Also, these formulations may change the biodistribution of the drugs, reduce drug resistance, diminish nonspecific toxicity and protect the drugs from enzymatic degradation [9,10]. Polymeric nanoparticles have been developed for various drug-delivery applications due to their biocompatibility, simplicity, and low cost of fabrication [11,12]. Currently, nanomedicine plays a central role in biomedical applications, such as diagnostic and therapeutic applications [12].…”