A Review on Non-Leaching Antibacterial Bone Cement for Orthopaedic Surgery: From Past to Current Insights
Zhe Gao,
Yu-Chen Kan,
Yang-Hu Xie
et al.
Abstract:Antibiotic-loaded bone cements are widely used in orthopedic surgery. However, they present issues such as a short antibiotic release time and the antibiotic resistance. These challenges necessitate the development of novel antibacterial bone cements. Non-leaching bone cement containing antibacterial motifs represents a promising advancement in this direction. Antibacterial motifs are incorporated into the cement either covalently or non-covalently, and while they will not be released, they will still exhibit … Show more
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