A Review on Medicinal Plants With Antidiabetic Activity From Rubiaceae Family

Abstract

Medicinal plants play an important role in the management of diabetes mellitus, especially in developing countries. A comprehensive review is conducted to accumulate information about medicinal plants with hypoglycemic properties. Rubiaceae represents one of five families of the most species-rich flowering plants. The Rubiaceae family is the largest plant family of 617 genera and about 13,137 species found worldwide, especially in the tropics and subtropics. Based on searches in several scientific journals, 617 genera of authors get about 34 species of plants that have antidiabetic activity. This review aims to provide information on the antidiabetic activity of the Rubiaceae family based on primary data from various literature and scientific articles collected by the search through online sites. The profile presented includes information on scientific and family names, plant parts and test models used, dosage and active chemicals. Information on antidiabetic medicinal plants can stimulate researchers to conduct further research on the potential use of medicinal plants that have antidiabetic potential.

Transformasi Genetik pada Kalus Embriogenik Tanaman Suku Rubiaceae

“…Suku Rubiaceae terdiri atas 10.700 spesies dan merupakan salah satu suku Angiosperm terbesar (Mongrand et al, 2005). Tanaman suku Rubiaceae telah lama digunakan dalam bidang kesehatan dan oleh masyarakat Indonesia untuk pengobatan tradisional (Sadino, 2018;Marusin et al, 2013), dimana beberapa diantaranya mampu menunjukkan efek antibakteri, antivirus, antiinflamasi, antioksidan dan analgesik (Heitzman et al, 2005). Kandungan kafein salah satu spesies tanaman Rubiaceae yaitu Coffea arabica banyak digunakan untuk obat migrain maupun untuk stimulan sistem saraf, diuretik, vasokonstriktor, dan bronchodilator (Simoes et al, 2004).…”

Elucidation of Bioactive Compounds in Methanol Extract of Mitracarpus Vilosus Leaf using GC-MS analysis

“…A review article on Mitracarpus spp (38) reported studies on phytochemical screening of the leaf extract of Mitracarpus vilosus which revealed potent saponin, steroids, and cardiac glycoside constituents (39,40). Ibrahim et al who explored the antibacterial efficacy of Mitracarpus vilosus extract on some selected multidrug resistance clinical isolates also reported the presence of saponin, tannins alkaloids, terpenoids, steroids, anthraquinones, flavonoids, and phenols in the acetone extract (41). Moreso, studies have shown that the presence of alkaloids, saponins, cardiac glycosides, and tannins were present in the ethanol leaf extract of M. scaber zucc which is another family of Mitracarpus sp.…”

Untitled

“…The secondary metabolites of the Rubiaceae family have a high medicinal potential, and this factor can be used as a marker for genera and subfamilies in chemical taxonomy [3]. Different species of this family have been investigated in terms of the potential for biological activities, such as antiplasmodial [4], antibacterial [5,6], antiinflammatory [7], and anti-diabetic activities [8]. The genus Crucianella is a flowering plant that belongs to the Rubiaceae family.…”