A Review on Eulophia nuda Immunomodulatory activity in Peritoneal macrophages and an assessment of its in-vivo activity in mice

Abstract

The purpose of this review is to highlight the findings of research on immunomodulatory activity of eulophia nuda tubers. Taxonomically, the genus Eulophia and the genus Dioscorea are represented in Amarkand. Pharmacologically, this plant has cytotoxic, antioxidant, antiglycation, and DNA protective activities. The selection of papers was made using the most relevant databases for the pharmacological activity on the basis of their phytochemical constituents. The review also goes over different in-vitro assay techniques and animal study conformation. The effect of Eulophia nuda extracts on the release of mediators such as nitric oxide (NO), superoxide, lysosomal enzyme, and myeloperoxidase activity of isolated murine peritoneal macrophages was studied at different doses. Eulophia nuda extracts were tested biochemically, hematologically, serologically, and histopathologically. The effect of eulophia nuda extracts on delayed-type hypersensitivity (DTH), serum antibody response, and cyclophosphamide-induced myelosuppression in Swiss albino mice was studied. The current work reviews the histopathological, biological, and statistical analysis of eulophia nuda extract on animal models.