A review on detection of heavy metals from aqueous media using nanomaterial-based sensors

“…New nanomaterials such as nanoclusters, aptamers, antibodies, and quantum dots are used in heavy metal detection systems. 25 , 29 Depending on the type of biosensor, it significantly increases sensitivity and specificity. Due to excellent resistance to oxidation and non-toxicity, gold nanoparticles are mostly used to manufacture biosensors applied in biotechnology and medicine.…”

Section: Application Of Nanomaterials In Biosensor Designingmentioning

confidence: 99%

Recent Advances in Nanotechnology-Based Biosensors Development for Detection of Arsenic, Lead, Mercury, and Cadmium

Maghsoudi¹,

Hassani²,

Mirnia³

et al. 2021

IJN

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Heavy metals cause considerable environmental pollution due to their extent and non-degradability in the environment. Analysis and trace levels of arsenic, lead, mercury, and cadmium as the most toxic heavy metals show that they can cause various hazards in humans’ health. To achieve rapid, high-sensitivity methods for analyzing ultra-trace amounts of heavy metals in different environmental and biological samples, novel biosensors have been designed with the participation of strategies applied in nanotechnology. This review attempted to investigate the novel, sensitive, efficient, cost-benefit, point of care, and user-friendly biosensors designed to detect these heavy metals based on functional mechanisms. The study’s search strategies included examining the primary databases from 2015 onwards and various keywords focusing on heavy metal biosensors’ performance and toxicity mechanisms. The use of aptamers and whole cells as two important bio-functional nanomaterials is remarkable in heavy metal diagnostic biosensors’ bioreceptor design. The application of hybridized nanomaterials containing a specific physicochemical function in the presence of a suitable transducer can improve the sensing performance to achieve an integrated detection system. Our study showed that in addition to both labeled and label-free detection strategies, a wide range of nanoparticles and nanocomposites were used to modify the biosensor surface platform in the detection of heavy metals. The detection limit and linear dynamic range as an essential characteristic of superior biosensors for the primary toxic metals are studied. Furthermore, the perspectives and challenges facing the design of heavy metal biosensors are outlined. The development of novel biosensors and the application of nanotechnology, especially in real samples, face challenges such as the capability to simultaneously detect multiple heavy metals, the interference process in complex matrices, the efficiency and stability of nanomaterials implemented in various laboratory conditions.

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“…The detection methods for heavy metal ions are various, including traditional methods and novel biosensors [ 7 ]. The traditional detection methods include atomic absorption/emission spectrometry, atomic fluorescence spectrometry, inductively coupled plasma mass spectrometry, high performance liquid chromatography and so on [ 8 – 12 ]. These methods can accurately quantify heavy metal ions with high sensitivity but they require professionals for on-site and routine environmental monitoring, and sample pretreatment is complex with expensive equipment, which limits their application [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Advances in aptamer screening and aptasensors’ detection of heavy metal ions

et al. 2021

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Heavy metal pollution has become more and more serious with industrial development and resource exploitation. Because heavy metal ions are difficult to be biodegraded, they accumulate in the human body and cause serious threat to human health. However, the conventional methods to detect heavy metal ions are more strictly to the requirements by detection equipment, sample pretreatment, experimental environment, etc. Aptasensor has the advantages of strong specificity, high sensitivity and simple preparation to detect small molecules, which provides a new direction platform in the detection of heavy metal ions. This paper reviews the selection of aptamers as target for heavy metal ions since the 21th century and aptasensors application for detection of heavy metal ions that were reported in the past five years. Firstly, the selection methods for aptamers with high specificity and high affinity are introduced. Construction methods and research progress on sensor based aptamers as recognition element are also introduced systematically. Finally, the challenges and future opportunities of aptasensors in detecting heavy metal ions are discussed.

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A review on detection of heavy metals from aqueous media using nanomaterial-based sensors

Cited by 128 publications

References 56 publications

Highly sensitive and selective colorimetric detection of dual metal ions (Hg²⁺and Sn²⁺) in water: an eco-friendly approach

Highly sensitive and selective colorimetric detection of dual metal ions (Hg²⁺and Sn²⁺) in water: an eco-friendly approach

Recent Advances in Nanotechnology-Based Biosensors Development for Detection of Arsenic, Lead, Mercury, and Cadmium

Advances in aptamer screening and aptasensors’ detection of heavy metal ions

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A review on detection of heavy metals from aqueous media using nanomaterial-based sensors

Cited by 128 publications

References 56 publications

Highly sensitive and selective colorimetric detection of dual metal ions (Hg2+and Sn2+) in water: an eco-friendly approach

Highly sensitive and selective colorimetric detection of dual metal ions (Hg2+and Sn2+) in water: an eco-friendly approach

Recent Advances in Nanotechnology-Based Biosensors Development for Detection of Arsenic, Lead, Mercury, and Cadmium

Advances in aptamer screening and aptasensors’ detection of heavy metal ions

Contact Info

Product

Resources

About

Highly sensitive and selective colorimetric detection of dual metal ions (Hg²⁺and Sn²⁺) in water: an eco-friendly approach

Highly sensitive and selective colorimetric detection of dual metal ions (Hg²⁺and Sn²⁺) in water: an eco-friendly approach