A Review on Analysis of Voriconazole.

Abstract

Voriconazole is a second generation triazole and is the result of a discovery programme aimed at improving the potency and spectrum of Fluconazole. The aim of this review is to focus on update of determination of Voriconazole in bulk and in pharmaceutical preparations using chromatographic and spectrophotometric methods. Voriconazole is estimated by RP-HPLC, UV, RP-UPLC, LC-MS methods. This review provides detailed information on separation conditions for Voriconazole alone, in the presence combination with other drugs and in presence of its degradation products.