A review on Active Constituents and Pharmacological Effects of Eriobotrya Japonica Lindl. (Loquat)

Abstract

Eriobotrya japonica Lindl., named as loquat, is a subtropical fruit tree of the family Rosaceae which is well known medical plant originated in Japan and China. Loquat portions, like leaves, peels and fruits have been shown to possess various health usefulnesses. In Chinese classical medicine, it is vastly utilized in many illnesses, like gastroenteric disorders, diabetes mellitus, pulmonary inflammatory diseases and chronic bronchitis. Loquat plant contain many active constituents, such as flavonoids, carotenoids, vitamins, polyphenolic compounds, other that have many biological effects like anti-tumor, anti-diabetic, anti-inflammatory, anti-mutagenic, antioxidant, antiviral, antitussive, hepatoprotective and hypolipidemic activity.

Antioxidant and Antiproliferative Activities of Phenolic Extracts of Eriobotrya japonica (Thunb.) Lindl. Fruits and Leaves

“…Components 10 , 14 , 18 , 24 , and 25 were recognized by comparison of their chromatographic and spectrometric data with commercially available samples as caffeic acid ( 10 ), quercetin 3- O -xyloside ( 14 ), kaempferol 3- O -rutinoside ( 24 ), and rosmarinic acid ( 25 ). Compounds 4 , 7–9 , 13 , 16 , 23 , 29 , and 33 were previously detected in this plant and, thus, identified by comparison of their UV–Vis and MS spectra with available literature as neochlorogenic acid ( 4 ), 3- O -coumaroylquinic acid ( 7 ), chlorogenic acid ( 8 ), cryptochlorogenic acid ( 9 ), ferulic acid ( 13 ), luteolin 7- O -malonylglucoside ( 23 ), dicaffeoyl quinic acid ( 29 ), and feruloylquinic acid ( 33 ) [ 1 , 17 , 18 , 27 , 28 , 29 ]. Compounds 1–3 , 5 , 6 , 11 , 12 , 17 , 26 , 31 , and 32 were predicted to be caffeic acid esters.…”

Phytochemical Analysis and Antifungal Potentiating Activity of Extracts from Loquat (Eriobotrya japonica) against Cryptococcus neoformans Clinical Isolates

“…The observed diversity of extracts in secondary metabolites can be explained by the difference in polarity of the extraction solvents used or by the part of the plant used. A broad range of important phytochemicals had been detected in loquat, like phenols, alkaloids, cardiac glycosides, flavonoids, mucilage, gums, and phytosterol [ 22 ]. The results of extraction yield ( Table 1 ) showed that the methanol with the highest polarity gave the highest yield of 8.5%, 6.68%, and 5.94%, respectively, in the seeds, leaves, and bark.…”