A review on a selected Ayurvedic herbal formula in the management of Kaphaja Unmada (Major depressive disorder): A critical analysis

Abstract

The widespread psychiatric disease known as major depressive disorder (MDD) is associated with a high rate of morbidity and mortality with correlation to Kaphaja Unmāda. According to family, twin and adoption studies, genetic variables are crucial in the emergence of MDD and may provide crucial details regarding the disease's pathophysiology. Bacopa monniera (Brāhmi) and Evolvulus alsinoides (Vishnukrānthi) were the ingredients of a decoction from a traditional formula and this review's objective was to investigate how well the herbal formula of decoction effective to treat MDD. Information about MDD and Kaphaja Unmāda was acquired from Ayurvedic scriptures, contemporary texts and earlier research studies (from primary and secondary sources). A survey of the literature was done on those two herbs in the selected decoction and then examined for their Pancha Padārtha (5 elements of herb) and pharmacological qualities regarding in the management of MDD. Ayurvedic Pancha Padārtha study has revealed that selected herbal formula has anti-depressant qualities because of their compatibility with Mēdhya (nootropic action) Prabhāva (special action). The majority of studies have demonstrated the anti-depressant effects of herbal formula, but reviewed articles have also highlighted additional qualities that aid in lowering the symptoms of MDD. According to the literature review and Pancha Padārtha analysis, selected herbal formula is useful in the treatment of MDD.